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13 Cards in this Set
- Front
- Back
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Phase 1 reactions |
Oxidation Reduction Hydrolysis |
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CYP enzymes important in anaesthesia |
2B6 2C9 2C19 2D6 2E1 3A4 3A5 |
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CYP with genetic variants |
2C9 2C19 2D6 |
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CYP2B6 |
Propofol |
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CYP2C9 |
Propofol S-warfarin Parecoxib |
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CYP2C19 |
diazepam Phenytoin omeprazole Clopidogrel |
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CYP2D6 |
Codiene flecainide Metoprolol |
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CYP2E1 |
Halothane Sevoflurane ISoflurane Paracetamol |
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CYP3A4 |
Diaz Temaz Midaz Fentanyl Alfentanil lignocaine/bupivocaine Vecuronium |
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CYP3A5 |
Midaz |
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Phase 2 reactions |
Gluconuridation Sulphation methylation N-acetylation. Hydroxylation |
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Inducer |
Rifampicin |
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Inhibitor |
Cimetidine. |
