Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
15 Cards in this Set
- Front
- Back
mutation on HFE gene on chromosome 6 (down regulating hepcidin) resulting in excess iron accumulation |
hemochromatosis |
|
toxic accumulations of copper associated with ATP7B gene on chromosome 13, mutated ATPase transporter |
Wilson's Disease |
|
mutation on chromosome 14 causing low levels of A1AT, increasing protease levels |
alpha one antitrypsin deficiency, presents concurrently with emphysema |
|
conjugated hyperbilrubinemia beyond 14 days of live |
neonatal cholestasis |
|
inflammatory autoimmune cholestatic disease in middle aged women with antimitochondrial antibodies |
Primary Biliary Cirrhosis |
|
diseases associated with Primary Biliary Cirrhosis |
Sjogran, scleroderma, RA, Raynaud, celiac |
|
obliterative fibrosis of extrahepatic bile ducts seen in middle aged males with a bead appearance and leaving a tombstone scar |
Primary Sclerosing Cholangitis |
|
thrombosis of major hepatic veins |
Budd-Chiari Syndrome |
|
chemo, bone marrow, bush tea cause endothelial toxicity and thrombi that block sinusoids |
sinusoidal obstruction sydrome |
|
central stallate scar with radiating fibrous septae |
focal nodular hyperplasia |
|
red-blue subcapsular nodules |
cavernous hemangioma- bleeding risk |
|
benign hepatocytic neoplasm from oral contraceptives |
hepatic adenoma |
|
Male dominated carcinoma assocaited with HBV and aflatoxin , elevated alpha-fetoprotein, dysplastic nodules |
hepatocellular carcinoma |
|
young adult cancer with single, large hard tumor in both sexes |
firbolamellar carcinoma |
|
hepatoblastoma, angiosarcoma |
FAP associated in childhood thorotrast, vinyl chloride, arsenic |