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15 Cards in this Set

  • Front
  • Back

mutation on HFE gene on chromosome 6 (down regulating hepcidin) resulting in excess iron accumulation

hemochromatosis

toxic accumulations of copper associated with ATP7B gene on chromosome 13, mutated ATPase transporter

Wilson's Disease

mutation on chromosome 14 causing low levels of A1AT, increasing protease levels

alpha one antitrypsin deficiency, presents concurrently with emphysema

conjugated hyperbilrubinemia beyond 14 days of live

neonatal cholestasis

inflammatory autoimmune cholestatic disease in middle aged women with antimitochondrial antibodies

Primary Biliary Cirrhosis

diseases associated with Primary Biliary Cirrhosis

Sjogran, scleroderma, RA, Raynaud, celiac

obliterative fibrosis of extrahepatic bile ducts seen in middle aged males with a bead appearance and leaving a tombstone scar

Primary Sclerosing Cholangitis

thrombosis of major hepatic veins

Budd-Chiari Syndrome

chemo, bone marrow, bush tea cause endothelial toxicity and thrombi that block sinusoids

sinusoidal obstruction sydrome

central stallate scar with radiating fibrous septae

focal nodular hyperplasia

red-blue subcapsular nodules

cavernous hemangioma- bleeding risk

benign hepatocytic neoplasm from oral contraceptives

hepatic adenoma

Male dominated carcinoma assocaited with HBV and aflatoxin , elevated alpha-fetoprotein, dysplastic nodules

hepatocellular carcinoma

young adult cancer with single, large hard tumor in both sexes

firbolamellar carcinoma

hepatoblastoma, angiosarcoma

FAP associated in childhood


thorotrast, vinyl chloride, arsenic