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20 Cards in this Set
- Front
- Back
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What is the morphology of Listeria?
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Intracellular, small, G+ rods
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What type of hemolytic reaction do the rods show?
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narrow zone of Beta-hemolysis
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What feature helps distinguish Listeria from streptococcus?
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Listeria are catalase positive
Streptococcus are catalase negative |
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What morphologic features do Listeria and Corynebacterium share?
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Nonspore-forming G+ rods
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What nonmorphologic feature distinguishes listeria from Corynebacterium?
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Listeria exhibits a tumbling motion and motility at room temperature
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What is the important pathogenic species of Listeria?
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Listeria monocytogenes.
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What populations are most commonly infected by Listeria?
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Pregnant women
Fetuses of infected mothers Immmunocompromised individuals |
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How do most people become infected with listeria?
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Via foot
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Does transmission from mother to child occur across the placenta or during the delivery?
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Transmission can occur in both situations.
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How does Listeria enter cells?
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Via phagocytosis
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How does Listeria penetrate the phagocytic vacuole to enter the cytoplasm?
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Pyroduction of listeriolysin O toxin
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Cell Listeria move from cell to cell?
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YES
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How does listeria move from cell to cell?
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Forms a "battering ram" by hijacking host cell actin to provide a portal of entry from one to another.
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What type of enymes aid in this passage across the cell membrane?
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Phospholipases
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What are three clinical manifestations of listeria?
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Meningitis
Sepsis Gastroenteritis outbreaks |
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What are two uncommon clinical manifestations of Listeria?
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Endocarditis
Lymphadenitis |
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How do infected mothers present?
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Flu-like illness or asymptomatically
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What is characteristic of gastroenteritis secondary to listeroisis?
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Watery diarrhea, fever, and headache
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How is the diagnosis of listeria infection usually made?
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Gram stain and culture
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What are the antibiotics commonly prescribed to treat listeria infections?
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Ampicililin and Gentamicin (esp. in newborns)
TMP/SMX and supportive care |
