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32 Cards in this Set

  • Front
  • Back
? causes of pink urine?
NB? drugs?
brick dust diaper/
drugs: rifampin/ibuprofen, nitrofurantion
+ RBC casts, dysmorphic RBC, cola colered urine
Proteinuria > 2;
where is blood from ? glom or non glomerular
glomerular; vs
non glom: eumorphic RBC, blood clots, red/pink urine
renal vein/artery thrombisis in mom ~ ?
infant of DM mom
abd mass, hematuria ! ?
wilm's
viral cystitis ~ ? virus
adenovirus
ghi ca/cr and hematuria?
hypercalciuia/lithiaisis
what drugs cause hematuria/problem in bladder and urethra?
cyclsphosphamide
? normal urine Ca/Cr to r/o hypercaluria?
nl < 0.22; in 24 hour > 4 mg/kg/day = hypercalcuiruia
? DX strep; PIAGN
ASOT, antiDNAse B
what's normal protein? vs proteinuria vs nephrotic?
nl: < 4 mg /m2/hr
Progetinuria: 4-40 mg/m2/hr
nephrotic > 40mg / m2/hr

urine Pr/cr: 6-24 mo - NL < 0.5
age > 2: nL < 0.25
3 yo boy, swollen eyes, diarrhea, edema of eyes, LE, and scrotum; urine 4+ protein; cholesterol: 470; b/L pleural effusions; HPM; decreased BS;
-albumin: 1.6; Cr 0.2; Na 127;
Dx? how dx? tx? what infx ~ ?
nephrotic
-lasix, steroids;
albumin; proteinuria > 40; low albumin;hi lipids;
path: no change, epithelial foot procesess
~ pnuemococcal infx/peritonitis
causes of Nephrotic?
minimal change
-FSGS
-MPGN
-membranous nephropathy
-congen nephrotic syndrome

Multisys: HSP, SLE, hodgkin's
8 yo boy swelling of eyes, legs, tired, HA;
urine cola colored; BP 150/85; edema of LE, increased vasc markings on CXR and enlarged heart;
-what h/o? cx/dx?
PIAGN: had strep throat s/p pcn: 8-14 days later;
-14-21 days > skin infx
-hematuria + proteinuria; HTN, HA, confusion, sz, oliguria;
Dx: low C3; NL C4; + ASO/ + Anti DNAase B
TX: fluid restrict, treat the Hi K/metabolic acidosis
what's urine findings and complements in PIAGN?
hematuria, RBC casts, leukocyturia; protineuria; low FeNA;
C3 LOW; BUT NL C4!!!; ;
blood: anemia; low albumin, hi K, low Na;
what will imaging of chest show?
cardiomegaly, pulm congestion, pleural effusion
How tx PIAGN?
early antbx (weakens) severity, but doesn't prevent
-fliud /salt restriction
-lasix for HTN;
-treat hyperkalemia
when does C3 return normal in PIAGN?
length of proteinuria and hematuria
6-8 wks;
hematuria gone: 6 mo
proteinuria: persist 1-2 yrs
10 yo girl w/ swollen eyes, pale; BP 145/80, protienuria, large blood 50-100 RBC/hpf;
-albumin 2.6; Cr 1.2 ; C3: 8 (nl 100); dense depositis in basement membrane; DX? TX?
membranoproliferative GN ( MPGN)
*KEY: low C3 aND C 4; ;
TX: steroids, then cytotoxic agents
Prognosis: 1/2 ESRD w/in 10 yrs; > 20 yrs: ESRD
What's most common GN?
-16 yo h/o URI, sore throat, red urine; HTN; proteinuria;
neg aNA; Cr 1.0; BUN 25;
-? complements show; Dx? Tx?
Ig A nephropathy; ** URI with HEMATURIA - same time: synpharyngitic hematuria;
-NL compleements;
dx: bx- mesangial depsits of Ig A**
* Hi IgA;
Tx: steroids
What 3 GN have low C3 ?
PMS:
PIAGN
MPGN
SLE
14 yo boy from Asia, leg swelling; foamy urine; HTN; 50-100 RBC urine; proteinuria; low albumin, hi lipids; Nl complements; subepithelial spikes along capillary wall;
~ hep B
membranous nephroapthy;
Tx: steroids
F , arthralgia, mucosal ulcerations; wt loss; CV; neuro; HTN; splenomegaly, LAD; pleurisy; alopecia; renal diz
-proteinuria; nephrotic syndrome; ? what serology get? Low C3
SLE;
+ ana, anti-ds DNA AB; hypocomplementemia; anti-sm AB; + RF
Tx: steroids
when is daytime and night time continence achieved?
~ 4 yrs; night : 5-7 yrs
what's most common abnl bladder problem?
overactive bladder
what are syndromes ~ kidney cysts?
von Hippel Lindau
-Tuberous Sclerosis
-Aq'd
-renal agenesis
which cystic diz involves both kidney and liver in childhood?
AR PKD: periportal fibrosis;
this presents later in life; abd masses, flank pain, hematuria; HTN; ~ TS, cerbral aneurysm, hepatic cysts - later in life;
ADPKD;
what's most common cause of Chronic kidney diz?
-usually males; prenatal U/s: B/L hydronephrosis w/ big bladder adn posterior urethra
- ? dx / tx?
PUV: post urethral valves;
-do VCUG;
tx: ablation
perineal /penile hematoma;
blood at meatus;
inability to void; ? How dx?
urethral injury;
dx: retrograde urethroagphy in males; females: cystoscopy
flank pain; hematuria, dysuria, N/V; + FH
Dx ? causes?
kidney stone;
CT - noncontrast (b/c will obscure stone);
causes: hypercalcuiria; hi oxalates, hyperuricosuria; cystinuria; CF
What's most common cz of HTN in kids?
renal: then
cardio: coarc
kid w/ HTN and cafe aulait spots; what's next test?
renal u/s; : NF1;