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9 Cards in this Set

  • Front
  • Back
apolipoprotein A-I
Activates LCAT
esterifies cholesterol, trapping it in HDL
used for formation of new HDL (all A's)
apolipoprotein B-100
Binds to LDL receptor
apolipoprotein C-II
Cofactor for lipoprotein lipase
found on VLDL, LDL -- HDL is circulating reservoir
apolipoprotein E
Mediates remnant (extra) uptake
(chylomicron)
apolipoprotein B-48
mediates chylomicron secretion
chylomicron
delivers (dietary) TG to peripheral tissue and (dietary) cholesterol to liver
secreted by intestinal epithelium
EXCESS: pancreatitis, lipemia retinalis, eruptive xanthomas
B-48, A, C-II, E
VLDL
delivers hepatic TG to tissues
secreted by liver
EXCESS: pancreatitis
B-100, C-II, E
LDL
delivers hepatic cholesterol to tissues
taken up in tissue by receptor-mediated endocytosis
EXCESS: atherosclerosis, xanthomas, arcus cornae
B-100
HDL
reverse cholesterol transport (tissues to liver)
repository for apoE and apoC (VLDL and chylomicron metab)
Secreted from liver and intestine
A-I, LCAT, CETP (transfer of cholesterol esters to other lipoprotein particles)