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14 Cards in this Set
- Front
- Back
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Four major physiologic roles of Fatty Acids in the cell
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• Building blocks of phospholipids and glycolipids
• Added onto proteins to create lipoproteins, which targets them to membrane locations • Fuel molecules - source of ATP • Fatty acid derivatives serve as hormones and intracellular messengers |
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Digestion occurs mainly in the...
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small intestine
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Fat particles are coated with what from the gall bladder?
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bile salts (they are amphipathic)
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Fat particles are degraded by....
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pancreatic lipase (hydrolyzes C-1 and C-3 to produce 2 fatty acids and 2-monoacylglycerol)
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After fat particles are degraded by pancreatic lipase, they are then absorbed by what cells in the small intestine?
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Intestinal epithelial cells; bile salts are then recirculated after being absorbed by the intestinal epithelial cells
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In the intestinal epithelial cells, fatty acids are converted to...
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fatty acyl CoA molecules
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phospholipids are hydrolyzed by pancreatic phospholipases, primarily...
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phospholipase A2
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Cholesterol esters are hydrolyzed by...
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esterases, to form free cholesterol. The free cholesterol is then solubilized by bile salts and absorbed by the intestinal epithelial cells.
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lipids are transported throughout the body as...
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lipoproteins
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Lipoproteins consist of....
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a lipid core (triacylglycerol, cholesterol, cholesterol ester) with amphipathic molecules forming an external layer.
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Lipoproteins are classified according to...
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their densities
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Which lipoprotein classification contains dietary triacylglycerols?
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chylomicrons
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Which lipoprotein classification contains dietary cholesterol ethers?
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chylomicron remnants
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Which lipoprotein classification transports endogenous triacylglycerols, which are hydrolyzed by lipoprotein lipase at the capillary surface?
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Very Low Density Lipoproteins (VLDLs)
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