Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
7 Cards in this Set
- Front
- Back
|
Statins - effects |
- Lowers TC and LDL - modestly increases HDL - HMG-coA reductase - side effects: muscle cramps |
|
|
Ezetimibe - mechanism |
Inhibits intestinal absorption of cholesterol and plant sterols |
|
|
Resins - effects |
- bile acid sequestrants - eg. Cholestyramine - lowers TC and LDL - ++ GI side effects |
|
|
Fibrates - mechanism, effects |
- eg. Gemfibrozil, fenofibrate - agonist of PPAR-a (regulates gene expression to influence lipid + lipoprotein metabolism) - lowers TG, modestly raises HDL-C |
|
|
Nicotinic acid - mechanism, effect |
- decrease fatty acid influx to liver + decrease VLDL secretion by liver - decrease IDL, LDL, increases HDL
|
|
|
Omega 3 fish oils- effects |
Lowers TG (which lowers TC) |
|
|
Cholesteryl ester transfer protein inhibitors - effects |
Increases HDL |
