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46 Cards in this Set

  • Front
  • Back

What are the cortical structures of the limbic system?

Form a ring around the medial aspect of the brain




Cingulate gyurs, parahippocampal gyrus, uncus and small areas in the hippocampal formation

What are the subcortical structures of the limbic system

Hippocampus


Amygdala


Septal Nuclei

What are the majot neural pathways of the limbic system?

Fornix


Mammilothalamic tract

What pathways does the fornix contain?

Interconnects the hippocampus to septal area, hypothalamus, and mammilary bodies




1) pathway to hypothalamus


2) major projection to mammilary bodies

What is the mammilothalamic tract

Connects the mammillary bodies with the thalamus




thalamus sens broad projections to the cingulate gyrus and other cortical areas

What is a major function of the limbic system?

Memory processing

What is the Circuit of Papez

Basic Pathway




Parahippocampal gyrus to




-Hippocampus


-Mammilary bodies


-Ant Thalamic Nuclei


-Back to parahippocampal gyrus vis the cingulum bundle

Where does the Circuit of Papez allow two way communication?

Prefrontal areas, premotor areas, visual, auditory and somatosensory association cortex.




forms basis for memory

What type of memory is Papez associated with?

formation of new memories - transition from short term to long term

What are the classification of memory?

Declarative memory


Nondeclarative (procedural) memory

What are the temporal aspects of the two memory types?

Immediate memory


Working memory


Long term memory

What is declarative memory

storage and retrieval that is available to consciousness and can be expressed by language

What is nondeclarative memory?

Memories that largely cannot be retrieved at a conscious level, how to preform tasks

What is immediate memory?

Ability to hold ongoing experiences in mind for fraction os a second.




-required to be oriented and responsive in an environment


-broad areas of cerebral cortex and their connection contribute to this


-It is evaluated clinically as a general orientation to environment

What is working memory?

Ability to hold information in mind for access for seconds to minutes after the present (short term)



What areas are involved in working memory?

Some is contributed by the hippocampus, maybe prefrontal cortex




Difference may be remembering how to use an item as well as what it is

What is long term memory?

The more permanent storage of information for periods of days, weeks, months or years.

What is consolidation

Process of converting information in working memory to long term memory

Describe declarative memory recall?

Involves a process of the reactivation of similar brain regions to those involved in perception.

What is forgetting?

The normal inability to convert memories from one form to another, loss ofm emory, or inability to recall

What is amnesia?

Pathological memory loss

What is anterograde amneisa?

Inability to form new memories

What is retrograde amnesia?

Difficulty retrieving memories already estabilished

Patients with isolated lesions of the papez circuit cause?

Patients have immediate and some short term memory but cannot consolidate information into long term memory.

What is the consolidation processes sensitive to?

Leisons of the hippocampus

Anoxia related memory loss

CA 1 area of hippocampus




Can become evident in cases where general body oxygen levels drop.

What can effect long term memory?

Diffuse damage of overactivation (epilepsy or electro therapy) can produce appreciable deficits in long term memory

Circuits for Non declarative memories?

Basal nuclei, prefrontal cortex, amygdala, sensory association cortex and cerebellum




NOT temporal lobe of midline thalamic nuclei

Most likely substrate for procedural memory?

Basal nuclei loops involved in the performance and integration of motor tasks.

What can diseases in which the basal nuclei are effected cause?

Huntingtons and Parkinsons



Inability to learn motor skills.

What can cerebellar damage interfere with?

Some types of conditioned reflex learning

What is Priming?

Phenomenon that demonstrates the continual transfer of information from working memory into long term memory whether or not there is an intent to remember it

When is priming particularly noted?

For the creation of associational biasing or creating false memories

What structures are involved in emotional memories

Amygdala, septal nuclei, nucleus accumbens, and the ventral tegmental area of the brainstem

Where is the amygdaloid complex located?

In the ant and med portion of temporal horn under the uncus with which part of it blends

What inputs does the amygdala use?

Visceral and somatic sensory inpus to coordinate emotional responses

What can electrical stimulation of the amygdala produce?

Feelings of fear or anxiousness

WHat is the amygdala connected to?

Directly and indirectly to septal areas, the hypothalamus, the nucleus accumbens and rostal a reas of the causdate nucleus and putamen




Large input from areas associate with taste and olfaction

Basic connections of amygdala are for?

Feeding and defensive behaviors

What does amygdala add to memory formation?

Sympathetic autonomic component and has properties of learning or modification with experience

Where is the nucleus accumbens

Lies at the jct of the causdate nucleus an the putamen and next to the septal nuclei

Where does Nucleus accumbens receive input from?

Amygdaloid complex, the hippocampal formation, and substantial nigra and ventral tegmental area

What receptors does the nucleus accumbens contain?

Receptors for a variety of neurotransmitters including endogenous opioids

What role does the nucleus accumbens play?

Addiction through the moderation of the rewarding nature of behavior

What are the outgoing connections of the nucleus accumbens?

To the hypothalamus, brainstem, and the globus pallidus.

Electrical stimulation of the nucleus accumbens may cause?

may be rewarding, and it may be responsible for the addictive or compulsive behaviors by attaching a positive affect to them