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66 Cards in this Set

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Limbic General Function Def.
Feelings, emotions, drive-related behavior important to survival
What portions of cortex is the limbic system?
Cingulate Gyrus
Parahippocampal Gyrus,
Subcallosal Area
Parts of the Limbic System
Cingulate/Parahippocampal Gyri
Amygdala
Hippocampus
Septal Nuclei
Hypothalamus
Reticular Formation
Olfactory
What part of the limbic system is the largest?
The Cingulate and Parahippocampal Gyri
What are the two limbic subsystems?
????????????
The Amygdala has three main areas within it. What are they?
Medial, Central, Basolateral
What are the amygdala areas and their function?
Medial, Central, Basolateral areas
The Medial Area of the Amygdala is associated with what input?
Olfactory (smell)
The Central area of the Amygdala is getting input from the _____ and _______ .
Brainstem (reticular formation)
Hypothalamus
The biggest Amygdala area in humans which is central to emotional response is the ________ .
Basolateral area of the Amygdala

Related to sensation input
The three inputs to the amygdala are:
Olfactory
Brainstem (RF) and Hypothalamus
Sensation input (vision, audio, taste, touch, thalamus)
The outputs of the amygdala include:
Thalamus, Cortex, Hippocampus, Hypothalamus, Brainstem, Ventral Striatum,
The Ventral Striatum has what function?
VS mediates reward and addiction properties
T/F. The Amygdala gives a positive or negative association with cortical information.
True. Amygdala tells us if something is like or not, good or bad.
The amygdala and hippocampus both are (inputs/outputs/both) to each other.
Both. They both are inputs and outputs to each other.
T/F. The fornix is the mostly efferent part of the amygdala.
False.

The Fornix is part of the Hippocampus and is made of axons.
The Hippocampus receives input primarily from the ________ cortex.
Entorhinal Cortex.

Also receives from other areas of cortex.
Outputs to the Hippocampus include:
Amygdala
Anterior Nuc of Thalamus
Mamillary Bodies of Thalamus
Hypothalamus, Septum, Ventral Striatum
The Fornix is mostly efferent and C-shaped.

The right and left ______ are connected by it.
Hippocampus.

The fornix is part of the hippocampus and connects both sides L + R hippocampi
The Amygdala connects to the Dorsomedial Thalamus and has what primary function in the Limbic?
The Amygdala is the Action Oriented System
-- initiates response
The Hippocampus projects to the Anterior Thalamic Nucleus and Mamillary bodies.
It's primary function is _________, _______, and ______.
Hippocampus is in charge of
Thought, Memory and Learning
Learning
Acquisition of New Information or Knowledge
Memory
Retention of Learned Information
Amnesia
Serious Loss of Memory and/or Ability to Learn

Can be Retrograde (don't remember past) or Anterograde (can't form new memories)
Engram
A physical representation or location of a memory

Memories aren't in a specific spot in the brain (spread out)
Dementia
Loss of previously held cognitive and intellectual functions without impairment of perception or consciousness
Declarative Memory
[explicit memory, can remember it]
Episodic Memory -- Experiences, Events
Semantic Memory -- Facts

These things are consciously recalled
Non-declarative / Procedural Memory
[implicit memory]
Skills and Behavior
"like riding a bike"
Three Functional Elements of Declarative Memory
(important for learning)
Acquisition
Storage
Retrieval

We can have dysfunctions in either of the elements.
Working memory is stuff we are actively trying to remember. If the information is consolidated, then it becomes long term memory.
True.
LTP = Long-Term Potentiation
Increased Use of Neurons
What portion of the brain is important for declarative memory
The Medial Temporal Lobe is CRITICAL for Declarative Memory
What are all the parts of the Limbic System?
Cingulate and Parahippocampal Gyri
Amygdala and Hippocampus
Hypothalamus
Setpal Nuclei
Reticular Formation
Olfactory
The Temporal Lobe hosts the:
Amygdala and Hippocampus
Sensory Stimuli Elicit Emotional Responses this elicits both involuntary and voluntary response.
True.

Voluntary and Involuntary
Feelings, emotions, and drive-related behaviors important to survival of the species."
Function of the Limbic
Limbic involves these parts:
Paraterminal Gyrus = Lamina terminalis
Parahippocampal Gyrus and Cingulate Gyrus
Subcallosal Area
Mam bodies
The Limbic System is composed of the telencephalon, diencephalon, and brainstem.
TRUE
Amygdala + Hippo = Cortex (telencephalon)
Hypothalamus = Diencephalon
Reticular Formation = Brainstem
The Control Center for the Limbic
Amygdala
The Amygdala Limbic Subsystem
Action Oriented System (Initiates Response)
Emotional learning/memory
Anterior portion of Limbic
Amygdala controls
The Hippocampus Limbic Subsystem
Thought, Memory, Learning System
Anterior Thalamic Nucleus and Mamillary Bodies
Posterior Portion of Limbic
Hippocampus controls
Amygdala Areas (3)
Medial -- Olfactory system
Central - emotional expression
Basolateral -- largest area, senses
Medial Area of Amygdala
Olfactory System
Input is Olfactory
Central Area of Amygdala
Important to Emotional Expression
INPUTS: Brainstem (reticular formation) and Hypothalamus
Basolateral Area of Amygdala
Info: Visual, Audio, Taste, Thalamus, Somatosensation
OUTPUTS OF AMYGDALA
Most go back to the Input
Hippocampus, Thalamus, Cortex, Hypothalamus, Brainstem(Reticular Formation), Ventral Striatum (reward)
Amygdala-Hippocampal Reciprocity
Both give each other input and output
Emotional Memory occurs in this structure.
Amygdala

Emotional learning also occurs here. With loss of Amyg, lose emotional content to memories.
Dementia
progressive
Loss of Cognitive Functions and Intellectual Functions
Disorientation, Poor Judgment
Can have memory affected (not always.
example is Alzheimer's
Engram
location or representation of a memory
Explicit Memory
Declarative Memory [facts and experience]

Easier to lose
Implicit Memory
Slow, Non-declarative, Procedural
"like riding a bike"

Harder to Forget
Learning
Acquisition of new info
3 Functional Elements of Memory
Acquire
Store
Retrieve

Can have a problem in each of the three
Sleep is important to consolidating memory.

If a memory is consolidated (sleep), it can move from working memory to __________ ____________.
Long-term Memory
Working Memory
Things we actively remember and try to store.
T/F. Nondeclarative memory is harder to form.
True. It's harder to make these memories but they stick around easier.
Non-declarative Memory Structures besides the Amygdala
Basal ganglia, Cerebellum, Neocortex
The source of episodic and semantic memory are located in what structure? Where is it located?
Hippocampus

Medial Temporal Lobe
Subconscious Reflexes located in the __________ .
Cerebellum
Medial temporal lobe is critical in ________ memory.
Declarative Memory
H.M. Case
Bilateral removal of Hippocampus and adjacent cortex
No new memory
Severe Anterograde Amnesia
No loss of procedural memory (could practice skills and not know it)
Hippocampus is Archicortex
3 Zones called:
Dentate Gyrus - 3 layered
Hippocampus Proper - 3 layered
Subiculum - transitional
Entorhinal Cortex is the primary input to the:
Hippocampus
Neurons that Fire Together, Wire Together.
Yup. That's it.
Why is LTP important for PT?
Repetition and Teaching Your Patient.

Patient Education