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14 Cards in this Set
- Front
- Back
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Lidocaine - Mode of Action
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Sodium channel blocker
– interrupts impulse conduction in peripheral nerves and stabilises excitable cell membranes |
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Lidocaine - Indications
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Local anaesthetic to reduce pain associated with:
- Intramuscular administration of ceftriaxone - Chest decompression in patients with GCS > 10 (MICA only) - Intraosseous administration of medication or fluid in a conscious patient (MICA only) |
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Lidocaine - Contraindications
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Known hypersensitivity to lidocaine or related
local anaesthetics Bupivacaine, Levobupivacaine, Prilocaine, Ropivacaine |
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Lidocaine - Precautions
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IM and local infiltration
- inadvertent intravascular administration may result in systemic toxicity (see below) IO –impaired CV function (e.g. hypotension, bradycardia, poor perfusion, heart block, heart failure) |
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Lidocaine - Adverse Effects
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Allergic reactions are rare and may present as localised oedema, urticaria, bronchospasm and anaphylaxis
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Lidocaine - Adverse effects
Signs of Systemic Toxicity - CNS |
Tinnitus
Blurred vision Sudden change in conscious state Agitation Convulsions |
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Lidocaine - Adverse effects
Signs of Systemic Toxicity - CV |
Hypotension
Bradycardia Arrhythmias (e.g. conduction blocks, ventricular tachyarrhythmias) Cardiac arrest |
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Lidocaine - Significant Interactions
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Nil
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Lidocaine - Preganancy
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Safe to use
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Lidocaine - Breastfeeding
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Safe to use
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Lidocaine - Presentation |
50mg in 5mL amp (1% solution) |
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Lidocaine - Route of Administration |
IM (when used to reconstitute ceftriaxone only)
Local tissue infiltration (for chest decompression) IO - infuse slowly over 120 seconds and allow to dwell for 60 seconds. Flush IO catheter with normal saline (5-10mL for adults, 2-5 mL for paeds) |
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Lidocaine - Onset and duration of action |
Onset 1-5 minutes (infiltration); 5-15 minutes(other routes) Duration 1-1.5 hours |
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Lidocaine - Notes |
Lidocaine and lignocaine are the same medication, but lidocaine is the preferred name internationally.
Both names will be in use in Australia until 2023. |
