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19 Cards in this Set
- Front
- Back
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spontaneous
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absence of known mutagen
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induced
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presence of known mutagen
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somatic
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non reproductive cells
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germ-line
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reproductive cells
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conditional
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restrictive conditions, think the cats
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unconditional
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permissive
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loss of function
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eliminates normal function
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hypomorphic (leaky)
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reduces normal function
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hypermorphic
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increases normal function
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gain of function
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wrong time or wrong cell type. ectopic expression
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base substitution
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one base replaced with another
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transition
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pyrimidine to pyrimidine (T or C) or purine to purine (A or G)
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transversion
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pyrimidine to purine
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insertion
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one or more extra
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deletion
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one or more missing
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synonymous (silent)
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no change in amino acid code
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missense
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change in amino acid encoded (non synonymous)
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nonsense (termination)
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translated termination codon UAA UAG UGA
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frameshift
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shifts triplet reading of codons out of correct phase
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