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23 Cards in this Set
- Front
- Back
what are smudge cells characteristic of?
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CLL
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what are numerous small, mature monoclonal B cells characteristic of?
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CLL
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what is a/w lymph nodes that become painful upon consumption of alcohol?
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hodgkin lymphoma
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what are the 3 B symptoms?
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weight loss of >10% in 6 mo.
night sweats fever >38 degrees |
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what are Reed Sternberg cells characteristic of
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hodgkins disease
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70% of what cancer are the "nodular sclerosing" type?
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hodgkins lymphoma
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in what lymphoma will you see eosinophilia in the blood?
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hodgkin's lymphoma
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describe the ann-arbour system of staging
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I - one node area
II - two or more node areas on teh same side of the diaphragm III - two or more node areas on differnet sides of the diaphragm IIIs - nodes and spleen IV - node areas as well as diffuse or disseminated disease subscript E is added at the end to indicate extranodal expansion |
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which leukemias are a/w the philadelphia translocation
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CML mainly
(although ALL can have it on occasion) |
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what is Gleevec used to tx?
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CML
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How does Gleevec work?
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It targets the bcr/abl abnormality, thus inhibiting tyrosine kinase activity which increases cell proliferation
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which is the luekemia where you need to give subdural prophylaxis?
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ALL b/c there are reserves in the CNS and the testes!
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which leukemia is a/w Down's syndrome?
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AML
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the presence of Auer rods indicates which leukemia?
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AML (it is the accumulation of myeloid granules) which distinguish it from ALL
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CLL is the same as which lyphoma?
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SLL - small lymphocytic lymphoma
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lymphoblastic lymphoma is the same as which leukemia?
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ALL
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for which leukemia is the treatment mainly palliative?
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CLL
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why do you use flow cytometry?
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to SUBTYPE a leukemia once the dx has been made
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what does CARLI stand for? And in what disease do you use this?
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Use it for characteristics of MM.
C- hi calcium due to increased bone turnover A- anemia (low RBCs) R- renal failure L - lytic bone lesions I - infxns due to suppression of normal plasma f'n |
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investigation of the CSF is required in work up of which leukemia?
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ALL
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Staging for lymphomas involves what 3 procedures?
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1. blood tests
2. bone marrow aspirate 3. CT scans of chest and abdomen |
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will lupus anticoagulant affect the PT or the PTT or both?
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only the PTT
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will heparin affect the PT, the PTT or both?
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the PTT only
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