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16 Cards in this Set
- Front
- Back
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Bone pain
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ALL
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Positive stains in ALL marrow biopsy
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CALLA/CD10, TdT, PAS
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Mediastinal mass
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ALL
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Philadelphia chromosome in 25%
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ALL
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M3 subtype of AML
M5 subtype of AML |
DIC
Gingival hyperplasia |
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Translocation and treatment of M3 subtype of AML
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t(15;17), treatment is all-trans retinoic acid
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Leukemia with symptoms of exertional dyspnea, renal vein thrombosis, confusion/somnolence, DIC
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AML - leukostasis. Treat with leukapharesis
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Average age of diagnosis is 65
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CLL
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Frequent infections, B symptoms
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CLL
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Autoimmune hemolytic anemia or autoimmune thrombocytopenia accompanies other symptoms
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CLL
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Smudge cells
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CLL
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Richter transformation
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CLL, transformation to lymphoma
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Lab abnormalities in tumor lysis syndrome, and treatment
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Elevated K, phosphate, uric acid; low calcium. Treatment is allopurinol and correction of electrolytes
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Massive splenomegaly
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CML
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Three phases of disease progression
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CML
Chronic phase - splenomegaly Accelerated phase - B symptoms Blast phase - >20% blasts, anemia, thrombocytopenia, etc |
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Strong association with Philadelphia chromosome (disease, translocation, treatment)
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CML
t(9;22) Gleevec/Imatinib |
