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49 Cards in this Set
- Front
- Back
defined as resistance to disease specifically infectious disease |
Immunology |
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studies the hosts reaction when foreign substances are introduced into the body |
Immunology |
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recorded that individuals who had previously contracted plague recovered and he recognized the IMMUNE status |
Thucydides |
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When and where did variolation started? |
10-15th century at China |
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Variolation can introduced to the body through? |
Inhalation and Skin Punctrue |
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She promoted variolation at England |
Lady Mary Wortley Montague |
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who are the people variolated at england |
4 yr old daughter of lady mary and 6 other condemned prisoners |
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small pox vaccination |
edward jenner |
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live attenuated chicken cholera and anthrax vacvination |
Louis pasteur |
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cellular theory of immunity through phagocytosis |
metchnikoff |
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humoral theory of immunity proposed |
vohn behring and kitasata |
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domenstration of cutaneous hypersensitivity |
koch |
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antibody formation theory |
ehrlich |
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arthus reaction of intermeditae hypersensitivity |
arthus |
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development of polio vacvine |
salk and sabin |
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vacvine against yellow fever |
reed |
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clonal selection theory |
burnet |
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1953 |
graft versus host reaction |
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1972 |
identification of antibody molecule |
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identification of genes for t cell receptor |
1985-1987 |
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1996-1998 |
identification of toll like receptors |
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Development of human papillomavirus vacvine |
frazer |
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who does edward jenner inoculated the cowpox lesion |
James phipp |
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where doed the dairy maid got the cowpox |
cows udders |
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inbolves administering LIVE PATHOGEN to develop immunity of the host |
variolation |
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involves administering of ATTENUATED WEAKENED pathogen to develop immunity of the host |
variolation |
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he observed that older bacterial culture would not cause disease in chickens |
louis pasteur |
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1894. complement |
jules bordet |
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opsonization |
wright and douglas |
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major histocompatibility complex |
baruj bencerraf. jean dausset. george shell |
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1984. HIV |
robert gallo |
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condition of being resistant to infection resistance to infectious agents,foreign particles, toxins, livibg cells, and cancers |
immunity |
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active immunity is acquired through vacvination of |
ANTIGEN |
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infuaion of plasma or serum containing high conc. of ANTIBODIES or lymphocytes from an actively immunized individual |
PASSIVE IMMUNITY |
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ability of individual to resist infection by normally present body functions |
INNATE OR NATURAL IMMUNUTY |
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characterized by specificity for each individual pathogen or microbial agent and the ability to remember a prior exposure which results in an increase response to that pathogen upon repeated exposure |
ADAPTIVE IMMUNITY |
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macromolecule that is capable of elliciting formation of ANTIBODIES or sensitized cells in an immunocompetent hosts |
Antigen |
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antibody is also known az |
immunoglobulin |
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epitobe is also known as |
determinant sute |
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antigen binding site |
paratope |
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small chain in an immunoglobulin molecule that is bound to the larger chain by disulfide bonds |
light chain |
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one of the polypeptide units that makes up an immunologic molecule |
heavy chain |
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each immunoglobulin chain is consists of |
2 heavy chain and 2 light chain |
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fragment of immunoglobulin molecule obtained by papain cleavage that consists of a light chain and one half of a heavy chain |
fab fragment |
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strength in which a multivalent antibody binds a multivalent antigen |
avidity |
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destruction if self reactive t and b cells as they mature in either the thymus or bone marrow |
central tolerance |
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destruction or repression of lymphocytes in the peripheral lymphoid organs that could repsond to self antigens |
peripheral tolerance |
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protein coded for by the human mhc gebes that ahs essential roles in the immune response and the rejection of foreign transplants |
human leukocyte antigen |
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cell surface molecules expressed on leukocytes and other cells relevant for the immunity system |
cluster of differentiation |