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49 Cards in this Set

  • Front
  • Back

defined as resistance to disease specifically infectious disease

Immunology

studies the hosts reaction when foreign substances are introduced into the body

Immunology

recorded that individuals who had previously contracted plague recovered and he recognized the IMMUNE status

Thucydides

When and where did variolation started?

10-15th century at China

Variolation can introduced to the body through?

Inhalation and Skin Punctrue

She promoted variolation at England

Lady Mary Wortley Montague

who are the people variolated at england

4 yr old daughter of lady mary and 6 other condemned prisoners

small pox vaccination

edward jenner

live attenuated chicken cholera and anthrax vacvination

Louis pasteur

cellular theory of immunity through phagocytosis

metchnikoff

humoral theory of immunity proposed

vohn behring and kitasata

domenstration of cutaneous hypersensitivity

koch

antibody formation theory

ehrlich

arthus reaction of intermeditae hypersensitivity

arthus

development of polio vacvine

salk and sabin

vacvine against yellow fever

reed

clonal selection theory

burnet

1953

graft versus host reaction

1972

identification of antibody molecule

identification of genes for t cell receptor

1985-1987

1996-1998

identification of toll like receptors

Development of human papillomavirus vacvine

frazer

who does edward jenner inoculated the cowpox lesion

James phipp

where doed the dairy maid got the cowpox

cows udders

inbolves administering LIVE PATHOGEN to develop immunity of the host

variolation

involves administering of ATTENUATED WEAKENED pathogen to develop immunity of the host

variolation

he observed that older bacterial culture would not cause disease in chickens

louis pasteur

1894. complement

jules bordet

opsonization

wright and douglas

major histocompatibility complex

baruj bencerraf. jean dausset. george shell

1984. HIV

robert gallo

condition of being resistant to infection


resistance to infectious agents,foreign particles, toxins, livibg cells, and cancers

immunity

active immunity is acquired through vacvination of

ANTIGEN

infuaion of plasma or serum containing high conc. of ANTIBODIES or lymphocytes from an actively immunized individual

PASSIVE IMMUNITY

ability of individual to resist infection by normally present body functions

INNATE OR NATURAL IMMUNUTY

characterized by specificity for each individual pathogen or microbial agent and the ability to remember a prior exposure which results in an increase response to that pathogen upon repeated exposure

ADAPTIVE IMMUNITY

macromolecule that is capable of elliciting formation of ANTIBODIES or sensitized cells in an immunocompetent hosts

Antigen

antibody is also known az

immunoglobulin

epitobe is also known as

determinant sute

antigen binding site

paratope

small chain in an immunoglobulin molecule that is bound to the larger chain by disulfide bonds

light chain

one of the polypeptide units that makes up an immunologic molecule

heavy chain

each immunoglobulin chain is consists of

2 heavy chain and 2 light chain

fragment of immunoglobulin molecule obtained by papain cleavage that consists of a light chain and one half of a heavy chain

fab fragment

strength in which a multivalent antibody binds a multivalent antigen

avidity

destruction if self reactive t and b cells as they mature in either the thymus or bone marrow

central tolerance

destruction or repression of lymphocytes in the peripheral lymphoid organs that could repsond to self antigens

peripheral tolerance

protein coded for by the human mhc gebes that ahs essential roles in the immune response and the rejection of foreign transplants

human leukocyte antigen

cell surface molecules expressed on leukocytes and other cells relevant for the immunity system

cluster of differentiation