Ler Notes

Front 1

Anminal bite

Back 1

Unasyn

Front 2

5 formulations of Erythromycin

Back 2

1. Erythromycin base
2. Erythromycin estolate
3. Erythromycin ethyl succinate
4. Erythromycin lactobionate (IV formulation)
5. Erythromycin ethyl succinate + sulfisoxazole
4. Erthromycin lactobionate

Front 3

Erythromycin base, generic?
(3A4 and 1A2 inhibitor)

Back 3

1. Ery-tab
2. E-mycin
3. Eryc

Front 4

Severe AE of Erythromycin estolate?

Back 4

Hepatoxicity

Front 5

Generic name of Erythromycin ethyl succinate?

Back 5

E.E.S. or EryPed

Front 6

What is Erythromycin lactobionate? one unusual reversibile AE?

Back 6

1. IV Erythromycin
2. Hearing loss

Front 7

what is the brand name of
(Erythromycin ethyl succinate + sulfisoxazole)?

Back 7

Pediazole, age > 2 months

Front 8

Kaletra

Back 8

Lopinavir/retionavir

Front 9

Minocycline
1. Generic name?
2. why does need to take it with fluids? (similar to Fosmax)

Back 9

1. Minocin or Dynacin
2. To decrease esophageal irriation

Front 10

1. Tri-PAK
2. Z-PAK
3. Zmax ( for acute sinuitis and community acquired pnumonia)

Back 10

1. Tri-PAK (500 mg #3)
2. Z-PAK (250 mg #6)
3. Zmax (2 g a single dose suspension form)

--- of azithromycin

Front 11

Azithromycin

Back 11

Zithromax, Zmax

Front 12

What does 2 g of Z-max is used for?

Back 12

gonorrhea
(not well tolerated --> vomiting; does must be repeated if vomiting occurs within hour)

Front 13

Avelox

Back 13

Moxifloxacin
(400 mg, brand only)
(risk of QT interval prolongation)

Front 14

What is transient toxicity from Minocyclin?

Back 14

transient vestibular toxicity

Front 15

4 Common consuling points for tetracyclines.
1.
2.
3.
4.

Back 15

1. Aviod sunlight (photosensitivity)
2. 2 hours before/4 hours after anacids, or Ca supplement(milk)
3. Avoid children and pregnant women (due to teeth staining)
4. Take with plenty of water (not milk) to avoid esophageal irritation

Front 16

Tigecycline

Back 16

Tygacil (related to minocycline)

Front 17

What is "Pediazole"?

Back 17

EES (erythromycin ethyl succinate + sulfisoxazole

Front 18

Isoniazid + Vit B6 ( 25 mg PO QD) --> ?

Back 18

To reduce the risk of peripherial neuropathy

Front 19

example of Class Ia ?-->

Back 19

procainamide

Front 20

example of Class Ib ? --> for ventricular arrthymia

Back 20

Lidocaine (CNS side effects)

Front 21

example of Class Ic ? --> cleaner drugs; avoid in CHF patients

Back 21

propafenone (Rythmol)

Front 22

example of class II -->

Back 22

propanolol (not beta-1 selective)

Front 23

examples of Class iV? -->

Back 23

Calcium channel blockers (CCBs)

Front 24

example of class III? -->
1) blocks K channeel

Back 24

prolonged refractory period

Front 25

adenosine

Back 25

adenocard

Front 26

acordarone; pacerone

Back 26

amiodarone

Front 27

disopyramide

Back 27

Norpace

Front 28

flecainide

Back 28

Tambocor

Front 29

Procanbid, pronestyl

Back 29

Procainamide

Front 30

Sotalol

Back 30

betapace

Front 31

Mexitil

Back 31

mexiletine

Front 32

Ibutilide

Back 32

Corvert

Front 33

felodipine

Back 33

plendil

Front 34

isradipine

Back 34

DynaCir

Front 35

nifedipine

Back 35

Procardia

Front 36

nisoldipine

Back 36

sular

Front 37

Calan. isoptin

Back 37

verapamil

Front 38

Hypothyrodism is low in T4 or T3?

Back 38

T4

Front 39

Amiodarone can cause hyper- or hypothyrodism?

Back 39

Hypothyrodism

Front 40

Frovatriptan

Back 40

Frova (Triptans: 5HT1 receptor antagonists; longest t 1/2 ~26 hours

Front 41

Licorice

Back 41

postmenopausal vasomotor symptoms

Front 42

Darvon ( C-IV)

Back 42

Propoxyphene (65 mg Tab)

Front 43

Darvon-N (C-IV)

Back 43

Propoxyphene (100 mg Tab)

Front 44

Darvocet

Back 44

Propoxyphene + APAP

Front 45

Darvocet N-50

Back 45

Propoxyphene + APAP
(50/325)

Front 46

Darvocet N-100

Back 46

Propoxyphene + APAP
(100/650)

Front 47

Darvocet A500

Back 47

Propoxyphene + APAP
(100/500)

Front 48

Olanzapine + fluoxetine

Back 48

Symbyax for bipolar indication

Front 49

Magmas = ?

Back 49

suspension

Front 50

w/o --> ?

Back 50

water in oil

Front 51

o/w --> ?

Back 51

oil in water (oil is internal phase)

Front 52

uroxatral®
Renal + Liver precautions
Affects QT interval

Back 52

Alfuzosin

Front 53

Cardura®

Back 53

Doxazosin (BPH and HTN)

Front 54

Minipress®

Back 54

Prazosin

Front 55

Flomax®

Back 55

Tamsulosin
a. Least orthostatic hypotension
b. Most ejaculatory problems
c. Preferred for the patients with poorly controlled angina, heart problems

Front 56

Hytrin®

Back 56

Terazosin (BPH and HTN)

Front 57

3 alpha1-blockers are related to 1st dose syncope?

Back 57

1. Doxazosin
2. Prazosin
3. Terazosin

Front 58

Symptoms of orthostatic hypotension are...

Back 58

1. dizziness,
2. hypotension
3. Postural hypotension
4. Syncope

Front 59

What are the 2 5-alpha reductase inhibiotrs?

Back 59

1. Avodart
2. Proscar

MOA: reduced prostate size (only indicated for enlarged prostate > 40 gm)

Front 60

Avodart

Back 60

dutasteride

Front 61

Proscar

Back 61

Finasteride

Front 62

What are the 5 alpha1-adrenergic antagonists?

Back 62

1. Alfuzosin (Uroxatral)
2. Doxazosin (Cardura)
3. Prazosin (Minipress)
4. Tamsulosin (Flomax)
5. Terazosin (Hytrin)

MOA: relax smooth muscle, improve urine flow and symptoms of BPH

Front 63

Name 3 rapid acting insulin are required Rx.

Back 63

1. Novolog
2. Apidra
3. Humalog

Front 64

Name 2 long-actinf insulin required Rx.

Back 64

1. Levemir
2. Lantus

Front 65

Which insulin canbe given SC/IM.IV?

Back 65

Regular

Front 66

Which insulin are cloudy.

Back 66

1. Humulin N
2. Novolin N
3. Mixtures

Front 67

Humalog, Novolog, Apidra are...

Back 67

Rapid-acting insullins

Onset: 10-15 nibutes

Front 68

What is Somogyi effect? Hyper- or hypo-glycemia?

1) S/Sx?
2) Tx?

Back 68

Rebound hyperglycemia

1) Low BS @3:00 am, cortisol released --> hyperglycemia
2) Decreased PM NPH dose, or eat a small snack at HS

Front 69

What is Dawn Phenomenon?

1) Tx?

Back 69

A rise BS between 0400-0800 am.

1) Increased NPH insulin, or move NPH to HS

Front 70

Red-book?

Back 70

List prescription, OTC and herbal drug products in the US and the average wholesale price (AWP), direct price and federal upper limit prices

Front 71

Orange book (Approved drug products with therapeutic equivalence evaluations

Back 71

1) bio-equivalency of generic products and NDC number

2) Check drug availablity

Front 72

which book?
"US and International approved names, chemical na,e, therapeutic use, dose..."

Back 72

Martindale

Front 73

Which book?

"Stability and compatibility"?

Back 73

Handbook on Injectable drug "Trissel"

Front 74

Which Book?

"Drugs in pregnancy and lactation"

Back 74

Briggs

Front 75

Which books for antmicrobial/antiviral?

Back 75

"Mandell"
"Vonte" and "The Sanford Guide"

Front 76

USP DI (drug information)
3 volume set.

1) Volume I
2) Volume II
3) Volume III

Back 76

1) DI for health professional
2) Information for patient
3) Approved drug products and legal requirements (similar to orange book)

Front 77

What is "ABC" book?

Back 77

Approved Bioequivalency Codes (updated monthly)

Front 78

What is chronic hypochlorhydria?

Back 78

Long-term use PPI. Gastric bacteria overgrowth

Front 79

Cimetidine + phenytoin -->DDI (?)

Back 79

Increased [phenytoin] thru inhibition of phenytoin hepatic metabolism

Front 80

Cimetidine + ketoconazole --> DDI (?)

Back 80

Decreased [ketoconazole] due to increased gastric pH

Front 81

Cimetidine + Tacrolimus --> DDI (?)

Back 81

Increased [Tacrolimus]

Front 82

What are the 2 drugs used to treat pain ass. with IBS?

Back 82

1. Dicyclomine (Bentyl)

2. Hyoscyamine (Levsin)

Front 83

What is Lubiprostone (Amitiza)?

USe: Idiopathic constipation in adult population

24 mcg capsule BID with food

Back 83

Cl- channel activators; open Cl- channels on apical (luminal) surface of GI epithelium

Front 84

Treatments for IBD.
1.
2.
3.
4.

Back 84

1. Aminosalicylates (5-ASA)
2. Corticosteroids
3. Immunomodulators
4. Biological therapy

Front 85

List 2 classes of meds are used to treat BPH.

Back 85

1. alpha-1 adrenergic receptor antagoinsts

2. 5-alpha-reductase inhibitors

Front 86

DHA (docosahexaenoic) and EPA (Eicosapentaenoic) are...

Back 86

Omega-3 FA

Front 87

Feverfew

Back 87

Prevention and treatment of migraine

Front 88

Licorice

Back 88

Treatment of PUD

Front 89

Drug recall classifications:
Cat I --> Cat III

Back 89

from the most serious to least serious

Front 90

FDA Limits

Antihistamine: no youner than ? y.o.

Back 90

< 6yrs

Front 91

FDA Limits

Inability to rinse Fluroide rine: no younger than ? y.o.

Back 91

< 6 yrs

Front 92

FDA Limits

Little need for the product: 1) Syrup of ipecac
2) sunscreen

no youner than ? y.o.

Back 92

1. < 6 months

2. < 6 months

Front 93

FDA Limits
Conditions refelcrs serious conditions:

1. KOH toothpaste

2. Hemorrhoidal tx

no youner than ? y.o.

Back 93

< 12 years old

Front 94

If pt is allergy to chrysanthemums, which OTC product pt should avoid.

Back 94

RID (Piperonyl butoxide + pyrethrins)

Front 95

Home UTI testing product is to detect ? ass. with G (-) bacteria.

Back 95

Nitrites

Front 96

What insulins are available OTC?

Back 96

Humulin R
Humulin N
Humulin 70/30

Front 97

Doses of actived charcoal.

1) < 1 yr
2) 1-12 y.o
3) >12 y.o

Back 97

1) 20-25 grams
2) 25-50 grams
3) 25-100 grams

Front 98

uric acid --> allantoin

by which enzyme?

Back 98

uricase

(allantoin is more soluble than uric acid)

Front 99

List drugs can increase uric acid levels.

1.
2.
3.

Back 99

1. Thiazide (increased uric acid reabsorption)

2. low dose ASA (decreased uric acid claerance)

3. niacin, PZA, ethambutol, and cyclosporin

Front 100

TXN for acute gouty attack.
1.
2.
3.

Back 100

1. NSAIDs (DOC)
2. colchicine
3. corticosteroids

Front 101

List 2 drugs lowering uric acid.

Back 101

1. Probenecid (preferred younger patients)

2. Allopurinol (perferred if Urinary excretion of UA > 1000 mg/day)

Front 102

Colchicine (starts within 12 hour gouty attack)

1) max PO dose? IV dose?
2) main AE

Back 102

1) Max PO: 8 mg/day, IV: 4 mg/day

2) diarrhea

(av

Front 103

Probenecid (Benemid)
INcreased uric acid excretion

Back 103

risk of gouty flare

- not effective for Crcl<50
- keep alkaline urine or plenty of flid intake

Front 104

Allopurinol (Zyloprim) not for acute gouty attack.

1) main AE
2) dose adjustment in transplant pt by? %
3) consul pts
DO not use durinf acut gouty attack

Back 104

1. Rash
2. 70%
3. drink plenty points

Front 105

Albuterol + Strattera --> DDI (?)

Back 105

Increased heart rate

Front 106

What is the
1. max dose of Strattera?
2. Initial dose for pediatrics?

Back 106

1. 100 mg/day

2. 0.5 mg/kg QD, and then 1.2 mg/kg/day (in divided doses)

Front 107

List 5 side effects of Strattera and stimulants?

Back 107

1. Dry mouth
2. Insomia
3. Increased heart rate and BP
4. Upset stomach
5. wt loss
6. headache

Front 108

List drugs aprroved for OCD in children.

Back 108

1. ZOloft

2. Luvox

Front 109

List 3 monitoring parameters for clozapine.

Back 109

1. agranulocytopenia
2. seizure
3. cardiomyopathy

Front 110

max dose:

1) IM Geodon
2) IM Zeprexa

Back 110

1) IM Geodon 40 mg/24 hours

2) IM Zeprexa 30 mg/24 hrs

Front 111

How often you give

1) Haldol Dec

2) Consta

Back 111

1) Q month

2) Q 2 weeks

Front 112

BBW for depakote.
1)
2)
3)

Back 112

1. Hepatotoxicity
2. tetragenicity
3. pancreatitis