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17 Cards in this Set
- Front
- Back
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genetic presdisposition for DM I
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HLA-DR3, DR4
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thought to be triggered by coxsackie B virus
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DM type I
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insulitis (inflammation of islets)
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DM type I
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amyloid deposition in islets
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DM type II
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most common cause of death in diabetes
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MI
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microvascular disease present in diabetes
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hyaline arteriolosclerosis
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diabetic nephropathy is a nephrotic or nephritic syndrome
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nephrotic
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pathognomonic kidney findings for diabetic nephropathy
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kimmelsteil wilson nodules
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diabetic nephropathy effect on basement membrane
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diffuse thickening
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diabetic effect on vasculature of eye
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microaneurysms
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3 effects of diabetic neuropathy
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peripheral neuropathy
neurogenic bladder sexual impotence |
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lesions of MEN I
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pituitary (prolactinoma)
parathyroids (hyper) pancreas (gastrinoma/insulinoma) |
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mutation of what gene is present in MEN I
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11q13
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lesions of MEN IIA
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parathyroid hyperplasia
pheo medullary ca of thyroid |
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lesions of MEN IIB
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oral neuromas
pheo medullary ca thyroid |
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mutation of what gene is present in MEN IIA and B
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RET
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number one cause of mortality in MEN I
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pancreas lesions (gastrinoma/insulinoma)
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