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10 Cards in this Set

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Excitation - Contraction Coupling

- Motor neuron conducts action potentials


- Action potential travels from the brain --> transferred to muscle fibre by structures called transverse tubles


- the T-tubules make contact with the sarcoplasmic reticulum (SR)


- excitation contraction coupling --> convert action potential to contraction --> calcium ions are responsible

Cross Bridge Cycle

- contraction of muscle has enough force to move the skeleton


- contraction occurs from many molecular events --> cross bridge cycle


- Cross Bridge: attachement of myosin with actin within the muscle


- Cross bridge cycling: repeated attachement of myosin and actin




Steps


1. Cross Bridge Formation: activated myosin head binds to actin, forming a cross bridge


2. Power stroke: ADP released and activated myosin head pivots


3. Cross Bridge Detachement: ATP binds to Myosin head making the bond between the head and actin weaker --> myosin head detaches


4. Reactivation of Myosin Head: ATP hydrolised to ADP and Inorganic Phosphate

Sarcromere

- Functional unit of contraction for striated muscle

How are muscles stimulated?

- by motor neurons


- each neuron may innervate many muscle fibers --> not all fibers are excited at the same time


- total force contraction depends on how many fibers are stimulated

Motor Unit

set of muscle fibers stimulated by single nerve fiber

Size of a Motor Unit

number of muscle fibers stimulated by a single motor nerve fiber

Precision of Muscle Response

governed by the size of the motor unit


- small muscles that react rapidly and with precision have small motor units


- large muscles that do not require a good degree of precision, have many muscle fibers in each motor unit

Action Potential

electrochemical signal generated by motor neurons

Isotonic Contraction

Constant Tention


- constant displacement


- latent period is small

Isometric Contraction

Constant Length


- longer latent period


- higher load, longer latent period