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62 Cards in this Set

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Subjective changes that are not apparent to an malais.


Example: malaise

Symptoms

Objective changes that physician can observe and measure

Sign

Group of sign and symptoms that accompany a disease

Syndrome

Any disease that spreads from one host to another.


Example: chickenpox, measles, genital herpes, TB

Communicable

Disease that are easily spread from one person to another.


Chickenpox & measles

Contagious

Do not spread from one host to another.


Example: clostridium tetani

Non-communicable

Number of people in a population who develop a disease during a particular time period

Incidence

Number of people in a population who develop a disease at a specified time, regardless of when it first appear ( both old & new)

Prevalence

Occurs occasionally

Sporadic

Occurrence of disease.


Base on frequency

Constantly present in a population

Endemic

Many people in a given are acquire a disease in a relatively short period of time

Epidemic

Epidemic disease that occurs worldwide

Pandemic

Develops rapidly & last only a short period ( influenza)

Acute

Develops more slowly, body's reaction is less severe, continue or recur for long period ( infectious mononucleosis, TB, HEPA B)

Chronic

Intermediate between acute and chronic ( panencephalitis)

Subacute

Causative agent remain inactive for a time but then becomes active to produce symptoms of a disease (shingles)

Latent

Invading microbes are limited to a relatively small area of the body ( boils and abscess)

Local infection

Microorganisms and their products are spread throughout the body by the blood or lymph ( measles)

Systemic/ generalized infection

Local infection ( teeth, tonsil, sinuses) that enter the blood or lymph & spread to specified parts of the body where they are confined to specific areas of the body

Focal infection

Acute infection that causes initial illness

Primary infection

Caused by opportunistic pathogen after the primary infection has weakened the body depended (PcP)

Secondary infection

Does not cause noticeable illness ( polio virus, HEPA A)

Subclinical

Interval between the Initial infection and the first appearance of sign & symptoms which depend upon pathogenicity and immunity

Incubation period

Relatively short period that is characterized by early, mild, symptoms of disease

Prodormal period

-Disease is severe in which the host exhibits overt sign and symptoms


-WBC may increase and decrease


- ACME- peak of illness intensity

Period of illness

Sign and symptoms subside

Period of decline

Person regains strength and body returns to prediseased states

Period of convalescence

Close physical contact between the source of disease and a susceptible host ( sexual contact)

Direct contact

Involves transmission of fomites ( inanimate objects)

Indirect contact

Transmission via droplet nuclei ( mucus droplets) in coughing or sneezing, laughing or taking

Droplet transmission

Transmission by a medium such as water, food or air

Vehicle transmission

Cary pathogens from one host to another by both mechanical and biological transmission

Arthropod transmission

Passive transport fr a vector's feet or other body parts

Mechanical

Reproduction of pathogen in a vector and transmission in saliva and feces

Biological

Acquired as a result of a hospital stay

Nosocomial infections

Impairs phgocytosis by producing chemical

Capsules

Heat and acid- resistant component of streptococcus pyogenes that helps the organism to resist phagocytosis of the WBC

M protein

Found in neisseria gonorrhoeae

Opa protein

Waxy lipid that makes up the cell wall of mycobaxterium tuberculosis

Mycolic acid

Producef by some staphylococci, forms clot that protect them from phagocytosis

Coagulase

Produce by streptococcus pyogenes and staphylococcus aureus ( breakdown fibrin)

Kinases

Produced by streptococci and clostria.

Hyaluronidase

Produced by clostridium species w/c breaks down collagen thus facilitates spread is gas gangrene

Collagenes

Produced by neisseria gonorrhoeae & N. Meningitis which destroys IgA antibodies

IgA proteases

- ability of the pathogen to alter its antigens, thud they become unaffected by the antibodies produced by the body


( influenza virus, neisseria gonorrhoeae, trypanosoma brucei gambiense)

Antigenic variation

The major protein of the cytoskeleton

Actin

Actin filaments of the cytoskeleton

Invasins

Glycoprotein which bridges the junctions in order for the bacteria to move from cell to cell

Cadherin

Protein secreted by the pathogens to obtained free iron

Siderophores

Poisonous substances produced by microorganisms

Toxins

Capacity to produce toxins

Toxigenicity

Presence of toxins in the blood

Toxemia

Depended present at birth which are always present and available for rapid responses; no memory response

Innates

Based on specific response to a specific microbes once a microbes has breached the innate immunity depenses

Adaptive

Vulnerabillity or lack of immunity

Susceptibility

Cardinal signs


Rubor

Redness

Cardinal signs


Pallor

Pain

Cardinal signs


Calor

Heat

Cardinal signs


Tumor

Swelling

Cardinal signs


Function leasa

Loss of function

Intense inflammatory response, cause is removed for a relatively short period

Acute inflammation

Cause is impossible or difficult to remove, inflammation response is longer lasting but less intense

Chronic inflammation