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17 Cards in this Set
- Front
- Back
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What could induce death in a patient receiving BZO?
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-given with other CNS depressants
-suicidal ideation -withdrawal syndrome |
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What could induce death in a patient receiving barbituates?
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withdrawal syndrome
overdose because of tolerance |
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What could induce death in a patient receiving TCA?
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cardiovascular disorders
fatal arrhythmias CV toxicity drug interactions if not wearing medical bracelet |
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What is the safe IV rate of delivery for BZO?
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Not exceeding 2mg/min
SLOWLY |
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What is first line drug therapy for depression?
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SSRI's (sertraline: Zoloft)
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What is second-line drug therapy for depression?
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TCA's
nortriptyline (Pamelor) |
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What is third-line drug therapy for depression?
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MAOI's
phenelzine sulfate (Nardil) |
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What is the MAOI diet?
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Avoiding tyramine and tryptophan
eg. aged meats and cheeses, salami, sausages, tap/nonpasteurized beers, soybean products, concentrated yeast extract |
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What is the lithium carbonate diet?
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Keep a constant level of sodium and fluid intake to avoid fluctuations in drug level
Avoid alcohol and caffeine |
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What are common antiepileptic drugs used for depression and bipolar disorder?
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carbmazepine (Tegretol)
valproic acid and divalproex sodium (Depakote) lamotrigine (Lamictal) |
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What is the advantage of using midazolam (Versed) in the ER for short procedures?
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quick onset
IV administration amnesiac effect conscious sedation |
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How do the acetylcholinesterase enzyme inhibitors increase cognition in patients with Alzheimers?
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They inhibit the action of Ach, which prolongs Ach activity on cortical cholinergic receptors and in the synapse.
Ach regulates memory and cognition DOES NOT alter course of dementia |
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In what primary body systems does rivastigmine (Exelon) cause adverse effects?
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GI
CNS CV |
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What level does lithium need to be maintained at? (mEq/L)
(therapeutic index) |
0.5-1.2 mEq/L
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What are positive symptoms of schizophrenia?
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Add a new layer to the person
hallucinations delusions |
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What are negative symptoms of schizophrenia?
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blunted emotions
lack of pleasure social withdrawal one-word answers |
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What is the difference between high and low potency typical antipsychotics?
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High: little sedation, little anticholinergic AE, high likelihood of causing EPS
Low: produce sedation, high likelihood of anticholinergic AC, low probability of EPS |
