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98 Cards in this Set

  • Front
  • Back

What is the second hardest substance in the body?





bone

What is bone composed of?


--Cells embedded in a matrix.




--Made of collagen fibers embedded in a protein and polysaccharides (poly = many, saccharides = carbohydrates)

What are the functions of bone?


--support


--protection


--leverage (for moving with muscle)


--homeostasis of calcium


--blood cell formation

Name 3 bone cells.


--Osteoblasts


--Osteocyte


--Osteoclasts

Bone cells--




What are osteoblasts?


cells that produce bone


Bone cells--




How do osteoblasts harden the matrix?


through ossification


Bone cells--




Once surrounded by bone (in the lacuna), osteoblasts are called _________.


Osteocytes

Bone cells--




What are osteocytes?


the most abundant cell in bone






Bone cells--




Osteocytes can become osteoblasts again to help with what?


reform new bone if needed

Bone cells--




What are osteoclasts?


remodel/remove bone


Bone cells--




What are osteoclasts important for?


calcium homeostasis

Bone structure--




Name two types of bones.


--Cancellous bone


--Compact bone


Bone structure--




Is cancellous bone light and spongy --or-- dense and heavy?


light and spongy


Bone structure--




Is compact bone light and spongy --or-- dense and heavy?


dense and heavy


Bone structure--




What is cancellous bone?




--tiny "spicules" of bone that appear randomly arranged.


--Reduces the weight of the bone with remaining strength


Bone structure--




In cancellous bone, the spaces between the spicules contain what?

bone marrow

Bone structure--




What is compact bone?


shafts of long bones and the outside layer of all bones


Bones structure--




What are compact bones composed of?


Haversian systems that run lengthwise with the bone


Bone structure--




What are Haversian systems (p. 175)?


concentric layers of ossified bone matrix arranged around a central canal


Bone structure--




What do the canals of the Haversian systems contain?


canaliculi which allow osteocytes to communicate with each other; also exchange nutrients and waste

Bone structure--




What is the periosteum?


membrane that covers outer surfaces of bones


Bone structure--




What is the outer layer of the periosteum composed of?


fibrous tissue


Bone structure--




What does the inner layer of the periosteum contain?


osteoblasts


Bone structure--




What does the inner layer of the periosteum do?


--allow bone to increase in diameter


--is involved in bone healing


Bone structure--




Is the periosteum present on articular surfaces?


no

Bone structure--




What is the endosteum?


--membrane that lines the hollow medullary cavity of bones


Bone structure--




Does the endosteum also contain osteoblasts?


yes

Blood supply to bone--




What are Volkmann canals?


Channels through bone matrix that contains blood vessels

Blood supply to bone--




Where are do the Volkmann canals run?


perpendicular to Haversian canals


Blood supply to bone--




What do blood vessels in the Volkmann canals joint with?


blood vessels in the Haversian systems

Blood supply to bone--




What does the Volkmann canal do?


bring nutrition to the osteocyte

What is ossification?


bone formation/hardening of matrix

Bone formation--




2 possible mechanisms of ossification


--endochondral ossification




--intramembranous ossification


Bone formation--




What is endochondral ossification?


grows into and replaces cartilage


Bone formation--




What is the most common bone development pathway?


Endochondral ossification

Bone formation--



What is intramembranous ossification?


--develops from fibrous tissue membranes




--example: the sutures in the skull


Endochondral bone formation--




primary growth center:




bones develop in the diaphyses

Endochondral bone formation--




What is the importance to the fetus?


cartilage is removed as bone is created


Endochondral bone formation--




secondary growth centers:


develop in the epiphyses of the bone (located at bone end)


Endochondral bone formation--




What are epiphyseal plates?

cartilage located between diaphysis and epiphyses of bone

Endochrondral bone formation--




What happens at epiphyseal plates sites?


--New bone develops to allow long bones to lengthen


--In long bone after birth is only cartilage in plates. As adult cartilage is replace by bone.


Endochondral bone formation--




What happens if epiphyseal plate is still growing and plate is broken?


It will stunt the growth


Endochondral bone formation--




What do osteoblasts do in epiphyseal plates?


Replace cartilage with bone on the diaphyseal surface of the plate.


Endochondral bone formation--




What happens to the epiphyseal plates when the bone has reached its full size?


they completely ossify


Intramembranous bone formation--




Where does it occur?


In certain bones in the skull


Intramembranous bone formation--




Where does bone form?


the fibrous tissue membranes that cover the brain in the developing fetus

Intramembranous bone formation--




What are mesenchymal cells?


type of stem cell that aggregate to the area (jump up)

Intramembranous bone formation--




What do mesechymal cells become?

osteoblasts

Intramembranous bone formation--




What do osteoblasts cluster to form?


osteoid


Intramembranous bone formation--




What happens to an osteoid?


it mineralizes or hardens

Intramembranous bone formation--




What will spicules of bone radiate out from?

ossification centers


Hormonal role on calcium levels--




What does calcitonin do?


lower the level of calcium in the blood and encourage it to be deposited in the bone

Hormonal role on calcium levels--




What is calcitonin triggered by?


elevated levels of calcium ion in the blood (hypercalcemia)

Hormonal role on calcium levels--




What is the opposite of calcitonin?

parathyroid hormone


Hormone role on calcium levels--




How are parathyroid hormones triggered?


deficient calcium levels (hypocalcemia)

Hormonal role on calcium levels--




What do parathyroid hormones stimulate?


osteoclast activity


Hormonal role on calcium levels--




Parathyroid hormones ________ calcium absoption in the intestines




increase


Hormonal role on calcium levels--




Parathyroid hormones ________ calcium excretion from kidneys.


decrease


Hormonal role on calcium levels--




Parathyroid hormones increase levels of ________ in the blood.


calcium


Bone shapes--




What are the 4 basic shapes?


1) Long


2) Short


3) Flat


4) Irregular bones


Bone shapes--




What are examples of long bones?


humerus, femur


Bone shapes--




What are examples of short bones?


carpal and tarsal bones (wrist bones)


Bone shapes--




What are examples of flat bones?


scapula, bones of the skull, pelvic bones


Bone shapes--




What are examples of irregular bones?


vertebrae, patella

Bone marrow--



What does bone marrow do?


fills the spaces within bones

Bone marrow--




What are the 2 types of bone marrow?


--red bone marrow




--yellow bone marrow



Bone marrow--




What is red bone marrow?

hematopoietic tissue (blood cell forming tissue)


Bone marrow--




What is the majority of the bone marrow of young animals?


red bone marrow


Bone marrow--




T or F: Red bone marrow is only a small portion of the marrow of older animals.


True


Bone marrow--




Where is red bone marrow confined to in older animals?


a few specific locations

Bone marrow--




What does yellow bone marrow primarily consist of?


adipose connective tissue


Bone marrow--




What is the most common type of marrow in adult animals?


yellow


Bone marrow--




Can yellow bone marrow revert to red bone marrow if needed?


yes

Joints--




What are the 3 general classifications?


--fibrous joints


--cartilaginous joints


--synovial joints



Joints--




Which joints are immovable (synathroses)?


Fibrous joints


Joints--




Which joints are slightly movable (amphiarthroses)?


cartilaginous joints


Joints--




Which joints are freely movable (diathroses)


synovial joints


Joints--




How are fibrous joints united?

by fibrous tissue


Joints--




What are examples of fibrous joints?


sutures of skull, splint bones of horses


Joints--




What are cartilaginous joints capable of?


slight rocking movement


Joints--




What are examples of cartilaginous joints?


mandibular symphysis, pubic symphysis, intervertebral disks


Joints--




A common characteristic of synovial joints is an articular surface on bones. What is this?


Thin smooth surface at ends of bones where they come together


Joints--




A common characteristic of synovial joints is articular cartilage (hyline covering articular surfaces). What does this allow?


smooth movement between those joint surfaces


Joints--




Synovial joints have a fluid-filled joint cavity enclosed by what?


a joint capsule


Joints--




What is the synovial membrane?


lines the joint capsule and produces fluid


Joints--




What does synovial fluid do?


lubricates the joint


Joints--




Synovial joints have ligaments. What are ligaments?


fibrous connective tissue that keeps joint in place while moving

Joints--




What are the 4 types of synovial joints?


--hinge joints


--gliding joints


--pivot joints


--ball and socket joints


Joints--




Synovial joints:




What are hinge joints capable of?


only capable of flexion and extension


Joints--




Synovial joints:




What is an example of a hinge joint?


elbow joint


Joints--




Synovial joints:




What are gliding joints?


rocking motion of one joint surface on the other


Joints--




Synovial joints:




What are gliding joints capable of?


primarily flexion and extension, but abduction and adduction are possible


Joints--




Synovial joints:




What are examples of gliding joints?


carpus (wrist)

Joints--




Synovial joints:




What are pivot joints?


one bone pivots (rotates) on another

Joints--




Synovial joints:




What are pivot joints capable of?


only rotation


Joints--




Synovial joints:




What are examples of pivot joints?


the atlantoaxial joint (between the atlas and axis)


Joints--




Synovial joints:




What are ball and socket joints?


allow for all joint movements


Joints--




Synovia joints:




What are examples of ball and socket joints?


shoulder and hip joints