Lecture 6 Salivary Gland Disorder

Front 1

what's this?

Back 1

Mucocele

Front 2

This is..

Back 2

Sialolithiasis

Front 3

this is

Back 3

Necrotising sialometaplasia

Front 4

what is this condition caused by?

Back 4

Sjögren syndrome

Front 5

What's this?

Back 5

Pleomorphic adenoma (PA)

Front 6

What's this?

Back 6

Mucoepidermoid carcinoma

Front 7

What's this?

Back 7

Ranula

Front 8

What's this?

Back 8

Plunging ranula

Front 9

Mucocele

Cause?

Back 9

Tissue swelling composed of pooled mucus escaped from a
severed salivary duct into the connective tissue.

Continued production of the saliva even after the severed duct and pooling results

Front 10

Mucocele

locations?

Back 10

lower lip and minor salivary glands

Front 11

Mucocele

Which is more involved?

major salivary glands or minor salivary glands?

Back 11

minor salivary glands

Front 12

Mucocele:

What's Ranula?

Back 12

If swelling appears in the floor of the mouth as a result of minor sublingual gland duct severance it's called Ranul

Front 13

Mucocele

What's Plunging ranula or mucocele?

Back 13

Mucocele that occurs due to severance of Wharton's duct (submandibular gland)

Front 14

Sialolithiasis

Cause?

Back 14

Due to salivary stones blocking duct

Front 15

Sialolithiasis

Which gland is affeted?

Back 15

submandibular gland

Front 16

Sialolithiasis

What's happens if the duct gets blocked?

Back 16

bacterial infection occurs

Front 17

Sialolithiasis

Age and sex?

Back 17

Average age = 45 years and no sex prediliction

Front 18

Sialolithiasis

Symptomatic?

Back 18

Yes

Pain and swelling, especialy during meal time

Front 19

Necrotising sialometaplasia

Cause?

Back 19

unknown

Front 20

Necrotising sialometaplasia

Location?

Back 20

Hard palate

Front 21

Necrotising sialometaplasia

Treatment?

Back 21

It will spontaneously heal

Front 22

Sjogren's syndrome

Common?

Back 22

uncommon

Front 23

Sjogren's syndrome

age and sex?

Back 23

elderley females

Front 24

Sjogren's syndrome

what is it?

Back 24

Autoimmune disease where the T-lymphocytes destroy exocrine glands

Front 25

Sjogren's syndrome

aetiologic factors?

Back 25

viral and genetic

Front 26

Sjogren's syndrome

what r the types?

Back 26

primary and secondary

Front 27

Sjogren's syndrome

Differentiate between primary and secondary SS

Back 27

if the disease only affects the lacrimal and salivary glands it's primary

if it is related to other autoimmune disease (eg. rheumatoid arthritis systemic, lupus erythematosus, scleroderma) it's secondary

Front 28

Sjogren's syndrome

clinical features?

Back 28

Xerostomia,
Difficulty eating
Soreness
Frothy viscous saliva

Front 29

What are the most popular benign lesions of the salivary glands in order?

Back 29

1st: Pleomorphic adenoma
2nd: Papillary cystadenoma lymphamatosum

Front 30

Papillary cystadenoma lymphamatosum

is AKA?

Back 30

Warthin tumour

Front 31

Papillary cystadenoma lymphamatosum

sex and age?

Back 31

male
6 to 7th decade

Front 32

Papillary cystadenoma lymphamatosum

lateral or bilateral?

Back 32

bilateral

Front 33

Pleomorphic adenoma

what kind of tumour?

Back 33

Mixed tumour
Wide variation in variation in parenchymal and stromal
differentiation

Front 34

Pleomorphic adenoma

Why the term "Pleomorphic" was given?

Is this valid? why?

Back 34

since it was thought the
growth originated from ‘multiple’ germ layers that give rise to ‘epithelial’ and ‘mesenchymal’ components of salivary tissue.

Now we know that, myoepithelial cell is present in periductal locations and has the ‘potential’ to ‘differentiate’ into “epithelial” and "connective tissue” cell types

Front 35

Pleomorphic adenoma

rate of growth?

Back 35

slow

Front 36

Pleomorphic adenoma

age and sex?

Back 36

3 to 5th decade
female 2: male 1

Front 37

Pleomorphic adenoma

Histology features?

Back 37

Pronounced fibrous capsule
Two dominant patterns: ‘medullary’ (diffuse sheets) and ‘trabacular’ (interlacing cords)

Front 38

Pleomorphic adenoma

Malignant transformation?

Back 38

less than 1%

Front 39

Mucoepidermoid carcinoma

types?

Back 39

high and low grade

Front 40

Mucoepidermoid carcinoma

age and sex?

Back 40

any age but peak 3rd 7th decade

females

Front 41

Mucoepidermoid carcinoma

which gland?

Back 41

50% in parotid

Front 42

Mucoepidermoid carcinoma

what's the uncommon malignant feature?

Back 42

may be movable

Front 43

Mucoepidermoid carcinoma: Histopathology

cell types?

Back 43

mucus
epidermoid
intermediate

Front 44

Mucoepidermoid carcinoma

Low grade has ____ ____ potential

Back 44

limited metastastic

Front 45

Mucoepidermoid carcinoma

What lines the cystic spaces?

Back 45

goblet mucus secreting cells
columnar ductal cells