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18 Cards in this Set

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  • Back
What is the definition of prognosis?
Prediction of the expected outcome of a disease with or without treatment
The greek definition of prognosis in greek is to come to know beforehand, how is this possible?
Use population data to make a prognosis
What are the 5 things that a prognosis should include (ideally)?
1) The variability in course relative to treatment options
2) A time reference
3) Risk of treatment-related death (or other untoward reaction)
4) Cost
5) Nature of benefit attainable
What is the definition of case fatality rate?
% of patients w/ a disease who die of it
What is the definition of survival rate?
% of patients surviving a defined period of time from some point in the course of their disease
What is the definition of response rate?
% of patients showing some evidence of improvement after an intervention
What is the definition of remission rate?
% of patients entering a phase in which disease is no longer detectable
What is the definition of recurrence rate?
% of patients who experience a return of disease after a disease-free interval
What are the 2 questions that are the rationale for the life table?
1) What is the likelihood of surviving for x years after diagnosis
2) What is the likelihood of surviving another year, given that the patient has already survived for y years since diagnosis
How do you calculte the cumulative probability of surviving different lengths of time?
It's a mutliplicative property so just multiple the probability of survival for each individual year
e.g. Probability of surviving 3 years= P1 x P2 x P3
What does a survival curve show
Cumulative survival over time
How do you compare multiple survival curves?
Steeper slope= worse survival
Why can the tail towards the right side of a survival curve be deceiving?
Beause as the population decreases even with the same survival rate it will look like a not very steep slope
What is the y-value of a survival curve?
Cumulative survival up to that time point
What does a survival curve show
Cumulative survival over time
How do you compare multiple survival curves?
Steeper slope= worse survival
Why can the tail towards the right side of a survival curve be deceiving?
Beause as the population decreases even with the same survival rate it will look like a not very steep slope
What is the y-value of a survival curve?
Cumulative survival up to that time point