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14 Cards in this Set
- Front
- Back
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_________ refers to a drug that relieves pain without loss of consciousness
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analgesic
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_________ refers to a drug that depresses the CNS, absence of all sensory modality, loss of consciousness
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anesthesia
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the ______ family is the most effective drugs for producing temporary analgesia and pain relief
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opioid
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name the three opioid peptides and their receptors
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beta endorphins---mu
enkephalins---delta dynorphins---kappa |
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in what 2 ways do the opioid peptides modulate nociceptive input?
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1. inhibit Ca2+ influx
2. open K+ channels |
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what is the "gate control" theory?
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non-noxious stimuli suppresses pain
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stimulation produced analgesia (SPA) works best on what 2 sites?
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PAG and raphe nuclei (RN)
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what is the opiate antagonist that blocks SPA?
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naloxone
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what substance is released during PAG/RN stimulation that acts to inhibit incoming sensory activity?
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serotonin (5-HT)
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what is the most effective method of producing OA?
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intracerebral injection of morphine into the PAG
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what nucleus do the PAG and RN have in common?
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nucleus reticularis gigantocellularis (RGC)
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T/F: bilateral lesions in the dorsolateral funiculus increase analgesia
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false (block the analgesia)
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opiate receptors are found on which Rexed laminae?
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I, II, and V
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what type of analgesia might athletes or soldiers experienced?
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stress-induced (SIA)
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