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15 Cards in this Set

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why do microorganisms like humans so much?
* constant source of nutrients
* constant source of moisture
* stable pH
* stable temerature
* extensive surface area
Endogenous infection
occurs when normal flora is introduced into a site that was previously sterile.
sterile body sites
blood, urine, CSF, liver, kidneys, brain, muscles, bone, ovaries/testes
non-sterile body sites
skin, upper respiratory tract, gastrointestinal tract, vagina, mucous membranes.
skin and mucous secretions
* spread in skin is slow, unless aided by scratching.

* moisture aids spreadon skin and mucous membranes.

* sneezing and coughing redistribute microorganisms on the mucous membranes (and into the enviroment)
lymph vessels
* microorganisms or their products can use the lymphatic system as a highway for transpotation around the body.

* some organisms multiply in the lymph nodes.

* swollen and tender lymph nodes are OFTEN the result of host-microbial interactions.
blood
* an excellent culture media and is often used in the lab to grow a number of organisms.

* some organisms can live and multiply inside red blood cells.

* some organisms prefer white blood cells.
Cerbral Spinal Fluid - CSF
* also an excellent culture media.

* infections that reach the CSF will quickly affect the brain and spinal cord and must be treated aggressively.
nerve tissue
* rabies virus and some microbial toxins affect nerve tissue.

* other nerves harbor latent viruses. ( chickenpox - shingles and other Herpesviridae)
muscle tissue
* Certain protozoa and viruses are attracted to muscle tissue.
- Trichinella spiralis
- Trypanosoma cruzi
Peritoneum
membrane lining the abdominal cavity, organisms entering can spread to many organs.
Pleura
membrane lining the chest cavity, organisms entering can spread along the surface of the lungs.
pathogen
a microbe whose relationship with its host is parasitic and results in infection and disease.
true pathogen
capable of causing disease in healthy persons with normal immune defenses.
opportunistic pathogen
cause disease when the host's defenses are compromised.