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17 Cards in this Set
- Front
- Back
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Describe the shape and position of the nucleus in:
Cardiac Muscle Smooth muscle Skeletal Muscle |
Cardiac - central nucleus
Smooth - central,corkscrew shaped nucleus Skeletal - peripheral nuclei |
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What is visceral striated muscle?
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Resembles skeletal but only found in soft tissues
tounge, pharynx, lumbar diaphragm, upper esophagus |
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What would you expect to see in a biopsy of a muscle suffering from Muscular Dystrophy?
Physical features of patient? |
Fat replacing muscle cells
Hypertrophic myofibers Large calf muscles |
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Where in the sarcomere to the triads occur?
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at A-I junction
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IN cardiac muscle cell sarcomere where do you find the t-tubules?
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at the Z disc
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What large organelle spans the distance between t-tubules
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mitochondria
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What part of the interclated disc is responsible for staining in H&E
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ZOnula adherens (fascia adherens)
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Do purkinje fibers have interclated discs?
describe purkinje cell |
no
large pale cells with lots of mitochondria |
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What do you measure to assess damage to cardiac muscle
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serum cardiac specific troponin
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Whats difference is present btw cardiac and skeletal muscle cells position of sarcoplasmic reticulum and t-tubules in relation to the sarcomere
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cardiac muscle cells have diads at z-disc
skeletal muscle cells have triads at A-I junction |
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Which has relatively more mitochondria cardiac or skeletal
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cardiac - 40%
skeletal - 2% |
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What is the Calcium binding protein fo Smooth muscle?
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Calmodulin
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What has the same function of Z-line (skeletal) in smooth muscle
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dense bodies
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What is the major intermediate fillemnt in smooth muscle cells
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Desmin
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Descibe smooth muscle cell contractrion
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Ca binds to calmodulin
Ca-Calmodulin activates myosin light chain kinase phosphorylation of head initiates contraction |
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What stimulates smooth muscle contraction of uterus during labor?
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Oxytocin
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Vascular smooth muscle is stimulated by
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passive stretch
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