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30 Cards in this Set
- Front
- Back
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immunity
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"free from burden"
protection of body from a disease caused by infectious agent innate adaptive |
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primary lymphoid system
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tissues that are responsible for generation of lympoid cells that respond to foreign antibodies
-bone marrow -thymus |
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bone marrow
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primary lymphoid
produce: eryhtrocytes platelets WBCs lymphocytes |
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secondary lymphoid system
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contirbute to innate (phagocytize), adaptive immunity
-lymph nodes -spleen -tonsils -appedix -peyer's patches |
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lymph nodes
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nodular tissue along lymphatic channels, react to antigens in lymph
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spleen
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responsible for reaction with Ag in blood
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tonsils
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contain lyphocytes that contribue to immune defenses
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appendix
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haven for useful bacteria when flushed away by illness
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peyer's patches
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major site of antibody production against mucosal pathogens
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blood
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60%, 40% cellular (RBC, WBC, platelets)
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leukocytes
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WBC
defensive in innate/adaptive 2 types- granulocyte (neutrophils, eosinophils, basophils), agranulocyte (monocyte, lymphocyte) |
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mast cell
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associated with allergy
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phagocyte
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big eater
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dendritic cells
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in spleen/lymph nodes, like phagocytes
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fibroblast
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produce CT, cytokines (immune resp)
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innate immunity
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natural defense of organ systems
-physical: skin, mucous membrane chemical: saliva, mucus, gastric juice, lysozyme |
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natural killer cell
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lymphocyte that kill intracellular viruses/cancer cells
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interferon
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molecular defense
protein enhances lymphocytes production of anti-viral protein |
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inflammation triggers
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physical: cut
chemical: acid/base biological: MO |
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cells in inflammation
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mast cell- histamine/prostaglandin prod
neutrophil- react quickly macrophage- engulf foreigners fibroblast- cytokine/CT prod |
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imflammation/healing process
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hemodynamic change: vasodilation
permeability change: swelling leukocyte changes |
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margination
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leukocytes adhere to blood vessel wall
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pavementing
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leukocytes adhere to capillary wal
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emigration
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leukocytes pass through blood vessel
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chemotaxis
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leukocytes that move toward chemical
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phagocytosis
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phagosome- organelle that holds foreign material
phagolysosome: phagosome + lysossome |
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clinical manifestations of inflammation
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-redness
-heat -swelling -pain -fever (100.5, very high- 104.5, fatal- 109; normal-98), induced by pyrogen |
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clinical measure to relieve inflamation
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-antihistamine
-aspirin/ibuprofen -icepack |
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accute
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untreated for days-weeks
host wins |
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chronic
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untreated for months-years
parasite continues to cause damage |
