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22 Cards in this Set

  • Front
  • Back

Friedrich Miescher

characterized proteins from pus cells

Friedrich Miescher

isolated a molecule from the nucleus and called it nuclein

Ernst Haeckel

who said : “the obvious cellular component of the cell is the nucleus” ?

Edmund Wilson

used staining technique to study karyokinesis of ovum



important nuclear element from cell to cell : DNA

Edmund Wilson

used staining technique to study karyokinesis of ovum



important nuclear element from cell to cell : DNA

Rosalind Franklin, Gosling & Maurice Wilkins

Found out that helical DNA structure, sugar, and phosphate background outside, while nucleotides are tucked inside

James Watson and Francis Crick

Found out about triple helix, and that phosphate is in the center (pero lol mali naman haha nice try gg)

Linus Pauling

proposed triple helix (epal)

John Griffith

Proposed that nucleotides are flat, stack up on top of another, and the possibility of A=T, C=G pairing.



Crick saw the importance of specific pairing in replication process.

Erwin Chargaff

proposed Chargaff’s rule



claims that purine-pyrimidine ratio is 1:1

Jerry Donohue

Claimed that hydrogen in the bases can change its position. (It may be responsible for the Hydrogen bonding)

Molecular Structure of Nucleic Acid



and



Genetic Implications of the Structure of Deoxyribuncleic Acid

2 Publications of Watson and Crick

James Watson, Francis Crick, and Maurice Wilkins



(Rosalind Franklin was robbed frfr)

Who were the ones who received a nobel prize?

Frederick Griffith

transformation experiment using Streptococcus pneumoniae



transformed avirulent strain to virulent



declared the presence of transforming principle

Oswald Avery, Colin Macleod, Maclyn McCarty

Physician-Scientists



identified the transforming principle (TP) as DNA

Alfred Hershey and Martha Chase

used the blender experiment



proved that the DNA is the genetic material of bacterial viruses which is injected into the cell during infection

Norton Zinder and Joshua and Esther Ledenberg

used transduction experiment in Salmonella typhimurium to further prove that DNA is the genetic material

Rosalind Franklin, Maurice Wilkins, James Wateson, and Francis Crick

Discovered the structure of the DNA



(elucidated the DNA structure)

Francis Crick

had PhD in Biophysics and worked on xray studies of proteins at Cambridge University

James Watson

PhD in Microbiology from Univ of Indiana then moved to Cambridge Univ. then shared office with Crick

Maurice Wilkins

PhD in Physics worked on radar and Manhattan Project and asst. Director of Med Research at Kings College, London



He worked on x-ray diffraction of DNA.

Rosalind Franklin

Expert on x-ray diffraction techniques and joined Kings College in 1951 to work on x-ray diffraction of DNA