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14 Cards in this Set
- Front
- Back
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MOA and use of methylcellulose
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absorbs water in colon - increases bulk - stimulates peristalsis
treats constipation and IBS-C |
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MOA and use of sodium phosphate
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osmotic effect to drag water into the GI tract - increases bulk - stimulates peristalsis
treats constipation (enema). Oral also for colon prep |
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MOA and use of lactulose
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osmotic effect to drag water into the GI tract - increases bulk - stimulates peristalsis
treats constipation |
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MOA and use of bisacodyl
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causes irritation to GI tract - activates enteric NS - stimulates peristalsis
treat constipation, add on to PEG for bowel prep |
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Which of the following would you use to evacuate the bowel prior to a colonoscopy?
methlycellulose lactulose docusate polyethylene glycol loperamide |
polyethylene glycol
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MOA and use of docusate
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surfactant that softens stool
use stool softener |
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MOA and use of loperamide and diphenolxylate
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binds opioid receptors on GI tract to reduce propulsive peristalsis and intestinal secretions
used for diarrhea |
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MOA and use of bismuth subsalicylate
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bismuth has some antimicrobial action
salicylate - inhibits PG production and reduces GI secretions used for diarrhea |
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Which agents works better for treating diarrhea?
lubiprostone methylcellulose docusate loperamide lactulose bismuth subsalicylate |
loperamide
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what is the difference between loperamide and diphenoxylate?
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diphenoxylate has low dose atropine to prevent drug abuse
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How fast will methylcellulose work in treating constipation
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slowly (12-24 hours)
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Main side effect of oral sodium phosphate
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acute phosphate nephropathy
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MOA and use of polyethylene glycol
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osmotic effect to drag water into the GI tract - increases bulk - stimulates peristalsis
treats constipation or used for bowel prep |
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MOA and use of lubriprostone
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activates Cl channel on gut to increase flux of Cl and hence water into the gut which increases mass and stimulates peristalsis. treats constipation and IBS-C
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