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30 Cards in this Set

  • Front
  • Back

Very fast muscle fibres need? Leaving less space for?

Lots of myofibrils,


Less space for other organelles

High force requires? Leaving less space for?

Requires lots of SR, less space for mitochondria.

3 ways slow fibres are different to fast

-Smaller diameter


-Darker color due to myoglobin (the haemoglobin of the muscle world)


-Fatigue resistant

Table of fibres type vs different kinds of activity (e.g. ATPase)

How much ATP per glucose do aerobic and anaerobic respiration provide? Which is fast/slow?

Aerobic- slow, but 36ATP per glucose



Anaerobic- fast, 2ATP per glucose (uses local energy stores)

CT cells: general functions of fibrocytes and macrophages

Fibrocytes: repair and maintain CT networks


Macrophages: scavenger cells that engulf both damaged cells and pathogens

2 things collagen is a major component of?

Tendons and ligaments.

6 cell types of CT proper

Fibroblasts, fibrocytes, mast cells (+lymphocytes, microphages), macrophages, adipocytes, mesenchymal cells.

What are mesenchymal cells?

CT specific stem cells

Where are dense regular and dense irregular tissues found?

Dense regular- in tendons and ligaments


Dense irregular- protective capsule around organs

What does dense regular tissue contain a lot of?

Fibroblasts

3 things formed in cytosol

Initiate peptides, polysaccharides, fatty acids.

What transiently attached ribosomes to ER

Initiate peptides

1 thing that happens to peptides in the ER and also in the golgi

Protein Glycosylation (addition of a carbohydrate)

2 things synthesised in peroxisomes

Bile salts and complex fatty acids.

What do glyoxisomes do?

Make sugar from fat via the glyoxylate cycle

2 things fibroblasts do

Secrete procollagen, which is cleaved for collagen


Secrete Hyaluronan, which forms a polysaccharide gel like base

What creates the supporting CT matrix? Out of what? (3)

Chondrocytes make the matrix



Thick gel like matrix of: proteoglycans, chondroitin sulfates and filaments.

What is similar about formation of reticular fibres and collagen fibres?

Both start with alpha helices

5 steps of signal recognition and transport into ER

1) Signal+ribosome binds to SRP


2) SRP binds to SRreceptor


3) Forms complex with translocon


4) Chaperon helps fold


5) SignalPeptidase cleaves signal

What do phosphotidylcholine membranes look like?

Cylindrical, more or less flat monolayers.

What is Zellweger syndrome?

Absence of all peroxisomes.

What is the type of phospholipid only normally found on inside leaflet

Phosphotidylserine

What kind of molecule are blood markers?

Glycosphingolipids

3 sources of ATP for muscle contraction

Phosphocreatine


Glycolysis


Oxidative phosphorylation

What's the tension-resistance relationship for isotonic contractions?

Isotonic: muscle tension peaks when it equals the amount of resistance

What's the tension-resistance relationship for isomeric contractions

Isomeric: resistance is greater than muscle tension capacity


Tension peaks at capacity, which is less than the resistance

Two types of isotonic muscle contraction

Concentric= pull


Eccentric= push

5 steps in skeletal muscle formation

1) specification- stem cells to myoblasts


2) proliferation and migration


3) fusion of myoblasts


4) formation of primary myotube


5) maturation into a muscle fibre

What surrounds: muscle fibres? Bundles of muscle fibres? Entire muscle?

Muscle fibres- endomysium


Bundles of muscle fibres- perimysium


Entire mistake- epimysium