Labs 15-18 Image Flashcards For Path Exam 3 (Dr. Laegreid)

Front 1

Back 1

Neutrophils adhering (margination) to a vessel wall with "rounding up" of endothelial cells in an edematous/inflamed tissue section.

Front 2

Back 2

Alveolar exudate consisting of numerous degenerated and necrotic neutrophils mixed with mainly fibrinous residues. Edema and leukocyte infiltration of interlobularar connective tissue.

Front 3

Back 3

Distended lymph vessel containing fibrinous clot.

Front 4

Back 4

Later phase of bronchopneumonia (macrophages are present and outnumber neutros).
Yellow = lymphocyte
Red = macrophage
Blue = neutrophils

Front 5

Slide 18

Back 5

Portion of lung with edematous and hemorrhaging alveoli (caused by bact. toxins)

Front 6

Slide 18

Back 6

Different portion of same lung with an alveolus filled with suppurative exudate.

Front 7

Slide 21

Back 7

Chronic Pneumonia
Thickening of walls with fibrosis (blue=collagen), macrophages (red) outnumber neutros (yellow). Alveoli lined with Type II pneumocytes (green) -- epithelialization.

Front 8

Slide 21 - Zoomed in

Back 8

Chronic Pneumonia
Thickening of walls with fibrosis, macrophages (red) outnumber neutros (yellow). Alveoli lined with Type II pneumocytes (green) -- epithelialization.

Front 9

Circulating Blood Cells

Back 9

green=neutro
purple=lympho
red=basophil
yellow=monocyte
blue=eosinophil

Front 10

What are these?

Back 10

Degenerating neutrophils in a suppurative exudate (pus)

Front 11

Pyometra

Back 11

Uterine gland filled with exudate of mostly neutros with some macros

Front 12

What organ is in the upper right and what is surrounding it?

Back 12

Saponified fat next to pancreas (with necrotizing pancreatitis) stimulating neutro influx

Front 13

Liver
What inflam cells are most seen here?

Back 13

Eosinophilic hepatitis due to migrating ascarids.

Front 14

What kind of leukocyte?

Back 14

Very intensely staining equine eosinophils in horse skin.

Front 15

What are these? (Giemsa stain)
Dog stomach

Back 15

Red=eosinophil
Green=mast cell

Front 16

Blastomyces dermatiditis lung infection (what sort of exudate?)

Back 16

Granulomatous pneumonia with macros filling the alveoli

Front 17

Back 17

Yellow=lymphocytes
blue=macros

Front 18

Back 18

plasma cells in canine small intestine

Front 19

Giemsa stain

Back 19

Mast cells and eosinophils

Front 20

Dog Lung
What kind of exudate?
How far has it progressed?

Back 20

Acute Pneumonia
Congested capillaries. Alveoli contain plasma proteinaceous fluid and neutrophils. Little stroma damage. complete regeneration possible.

Front 21

Lung
What kind of exudate?
What shows that this inflam. has progressed further?

Back 21

Fibrinopurulent exudate.
Pneumonia inflammation has progressed to the point where fibrinogen has leaked out. Mix of fibrin and neutros.

Front 22

dog lung
Characterize exudate

Back 22

Consolidation: all alveoli filled with suppurative exudate. Lung would feel solid.
Lots of necrotic neutros and some fibrin.

Front 23

Cow lung
What stage?
Why?

Back 23

Chronic pneumonia with thickened, collagenous interlobular septa. (fibrous scarring and proliferation caused by the chronic irritation)

Front 24

Cow

Back 24

Enlarged lymph node (4-5x normal) from receiving lymph from inflamed lung.

Front 25

Dog kidney

Back 25

Inflamed glomerulus

Front 26

Dog kidney

Back 26

Interstitial nephritis - leukocyte infiltration of the interstitium (lymphos, monos, plasmas) due to leptospira ---> leads to interstitial fibrosis and parenchymal atrophy

Front 27

Cow kidney

Back 27

Chronic pyelonephritis -
Thick white fibrous capsules around the dilated calyces (which contain dried pus)

Front 28

dog kidney

Back 28

Both hydronephrosis (the dilation) and pyelonephritis (the suppurative exudate.

Front 29

Pig Lung

Back 29

Mycoplasma pneumonia
Bronchioles contain thick mucinous material.

Front 30

Rabbit Intestine
What sort of exudate?

Back 30

Catarrhal Enteritis
Mucous plugs from irritation of mucosa.

Front 31

Cow intestine
PAS Stain
What is this substance?

Back 31

Catarrhal Enteritis
PAS stain showing the polysaccharides in the excessive mucous. Almost the whole mucosa has been converted to mucin producing cells.

Front 32

Cat thorax
Characterize exudate

Back 32

Serous exudate in chest and pericardial sac due to inflam. of pleura and pericardium.

Front 33

cat intestine
What is this substance on the mucosa?

Back 33

Fibrinous enteritis
(fibrinogen has leaked out of vessels due to extensive inflammation and vessel damage) - this is viral

Front 34

cow trachea
what is this?

Back 34

fibrinous tracheitis
caused by bact. inf

Front 35

cow resp. tract

Back 35

fibrinous bronchitis
large yellow clots may occlude the bronchi

Front 36

Pig abdomen
What is going on here?

Back 36

Fibrinous Peritonitis
Fibrin deposits and adhesions all over viscera. Some is being replaced by fibrous scar tissue ("organized")

Front 37

Cow thorax

Back 37

Fibrinous pleuritis
Severe. Parially organized adhesions

Front 38

Cow abdomen

Back 38

Fibrinopurulent exudate.
Caused by bact. inf. due to stomach penetration (foreign body)

Front 39

Cow heart
What kind of inflam. and for how long?

Back 39

Chronic fibrinopurulent inflam of the epicardium
Due to "hardware disease"

Front 40

Cow abd. viscera

Back 40

Fibrinopurulent peritonitis
Blue = fluid exudate
green = fibrin covering omentum (suppurative)

Front 41

Cat abdomen

Back 41

FIP - fibrinopurulent peritonitis
Moderate suppurative response with fibrinopurulent clumps

Front 42

Cat liver
What has caused these changes?

Back 42

fibrinous hepatitis
due to FIP

Front 43

Dog uterus
Characterize exudate

Back 43

Severe purulent metritis
pan is filled with pus

Front 44

dog lung

Back 44

Consolidation of dog lungs
Purulent bronchopneumonia with alveoli completely filled

Front 45

Cat thorax
What kind of exudate/inflam?

Back 45

severe suppurative pleuritis
(pyothorax)

Front 46

Cow brain
What kind of inflam and what cell mainly?

Back 46

Suppurative encephalitis
Micro abscesses
Mostly neutrophils

Front 47

Horse lung

Back 47

Suppurative pneumonia with many large caseous abscesses (encapsulated)

Front 48

Dog intestine

Back 48

Hemorrhagic enteritis and hemothorax due to severe hook infestation

Front 49

Cow bladder

Back 49

Mucosal epithelium loss and fibrinous sanguinopurulent exudate accumulation.
"The exudate is primarily a combination of necrotic neutrophils, cell debris and red blood cells trapped within a fibrin meshwork."

Front 50

Chicken trachea
What is this change called?

Back 50

Tracheal Pseudomembrane
Viral. Necrotic portions of the mucosa are covered and enmeshed in a heavy fibrinous exudate

Front 51

Pig intestine

Back 51

Pseudomembranous (fibrinonecrotic) enteritis.
Caused by salmonella

Front 52

Pig colon (histologic)

Back 52

Pseudomembranous colitis (necrotizing enteritis)
The bottom shows the necrotic layer enmeshed in fibrin from the inflam. response of the underlying living tissue. A lymph vessel is trying to drain away all the fibrin.

Front 53

pig colon
What two sorts of change do you see here?

Back 53

some pseudomembrane has sloughed off, revealing the ulcerated hemorrhagic mucosa underneath (blue). the other parts of colon are very congested (green)

Front 54

Dog pancreas
What stage of disease is this?

Back 54

Chronic pancreatitis
Mature connective tissue has replaced a lot of the parenchyma

Front 55

Cow liver
How long?

Back 55

Chronic hepatitis
lots of mature connective tissue (scarring)

Front 56

Cow liver

Back 56

extensive loss of parenchyma with fibrous tissue replacement (hepatic fibrosis)

Front 57

Pig liver (and lungs)

Back 57

Fibrosis of liver due to larval migrans (eosinophilic inflam infiltrated by connective tissue)
Also, multifocal pneumonia with hemorrhage

Front 58

Dog Kidney
How long?
Explain outward appearance of the kidney

Back 58

Chronic glomerulonephritis
Grey lines of fibrous tissue on cut surface. The uncut surface is pitted and irregular due to contraction of the scar tissue.

Front 59

Dog kidney

Back 59

Chronic nephritis due to pyelonephritis
Kidney is pale, irregular, and firm

Front 60

cat abdominal cavity
What happened and what is covering everything?

Back 60

Chronic peritonitis
Thick covering of fibrous tissue that has contracted, shrinking the organs

Front 61

Cow - Fibrotic Lung
What could this lead to?

Back 61

Passive congestion of liver
(beneath lung)

Front 62

Pig liver

Back 62

Encapsulated abscesses and diffuse fibrosis due to corynebacterium infection.
(pseudotuberculosis)

Front 63

Sheep liver

Back 63

Caseous mass with thick connective tissue capsule
(due to corynebacterium (pseudotuberculosis))

Front 64

Pony
What kind of tissue is this? (healing)

Back 64

granulation tissue
see that fibroblasts (pink) are perpendicular to capillaries (green).
Lots of collagen as you get deeper.

Front 65

Cow rumen

Back 65

Proliferation of connective tissue in mucosal nodules due to chronic inflammation.

Front 66

Pony

Back 66

Deep granulation tissue
Perpendicular orientation of fibroblasts and capillaries no longer apparent. Not very cellular with a lot of collagen.