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80 Cards in this Set
- Front
- Back
define cervical effacement
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process by which uterine activity causes the cervix to be drawn intrabdominally into the lower uterine segment. it is also known as the thinnning or shortening of the cervix
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labour
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repetitive uterine contractions associated with progressive cervical effacement and dilatation
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what is the length of human gestation
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280 days
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T or F a decrease in maternal progesterone is not seen at the onset of labor
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t
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role of PG in labor
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PGE2, PGF2 alpha
PG is produced in the endometrium myometrium and chorioamnion arachidonic acid, a precursor to PG is stored in cell membranes labor triggers release of arachidonic acid and under the influence of COX is converted to PG |
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PGE2 role in cervix
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PGE2 and relaxin induce changes in cervix associated with cervical repening
↑collagen lysis and ↑ wateraccumulation, resultng in softening ↑ distensibility of the cervix |
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PGF2 role in uterus
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it is a potent stimulator for uterine contractions
-receptors for it are found in myometrial cell membrane and in sarcoplasmic reticulum ↑ in intracellular calcium as it is released from sarcoplasmic reticulum and from outside sources high intracellular calcium enables the sliding of actin and myosin- allowing myometrial contractions |
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why are PGE2 analogues used
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used as cervical repening agents
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why are PG synthase inhibitors used
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to stop preterm labor- tocolytic
Indomethacin |
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what is oxytocin
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it is a prohormone stored in posterior pituitary
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what happens to oxytocin receptors near term
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increases
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sensitivity of uterine muscles to oxtocin _____ near term
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increases
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low levels of oxytocin present throughout pregnancy but only increase significantly when __________
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labor has begun
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oxytocin release from the post pit is caused by various stimuli including:
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distension of birth canal as baby moves through it
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where does oxytocin bind
and what does it activate |
oxytocin binds to oxytocin receptors on uterine muscle cell membrane
IP3 and DAG, IP3 induces release of calcium from sarcoplasmic reticulum |
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why is synthetic oxytocin used
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to enduce or augment labor
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what does ethanol due to oxyocin release
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inhibits it- tocolytic
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oxytocin antagonis can be used as a ______
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tocolytic
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what are the 4 stages of labor
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1st stage: time from onset of labor to full dilatation of the cervix
2nd stage: time from complete dilatation of the cervix to birth of the baby 3rd stage: time from birth of baby to delivery of placenta 4th stage: time from delivery of placenta to stabilization of patient- 6hrs postpartum |
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name 2 phases of the first stage of labor
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latent phase,
active phase |
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Define latent phase: 1st stage
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little appears to be happening
but contractions more coordinated, stronger and efficient cervix softening, effacement, early dilatation, and movement from anterior to posterior latent phase shorter in multiparous - 8 vs 5 |
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define active phase 1st stage
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begins when cervix is 3-4 cm dilated
dilatation occurs more rapidly faster in multiparous 6 vs 3 |
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duration of 1st stage
multi and nulli |
6-18 nulli
2-10 for multi |
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what is extent of cervical effacement
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2-3 cm to paper thin
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measurement of progress of the delivery is by
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cervical effacement, dilatation, consistency of the cervix, position of cervix and descent of fetal head
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range of dilatation
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1-10 cm
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range of consistency
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firm, medium, soft
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range of cervical positions
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in relation to vagina
posterior, midposition, anterior |
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descent of the fetal head
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only occurs after full dilatation and in 2nd stage
once it begins it should be progressive measure by stations |
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stations
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relationship of presenting part of infant to an imaginary line between ischial spines
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partogram
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way to mark progress in dilatation and descent
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3 PS OF MEASUREMENT OF PROGRESS
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power passage and passenger
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power - what can be done to improve it
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if power of contraction is suboptimal can be improved by amniotomy if membranes are still intact
and oxytocin augmentation |
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passage
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passage or shape of maternal pelvis cannot be altered
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what are the 4 basic types of pelvis?
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gynecoid
android anthropoid platypelloid |
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which two pelvis shapes are most conducive to labor
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gynecoid and anthropoid
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maternal obesity _______the likelihood of vaginal delivery
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decreases
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cephalopelvic disproportion
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exists when maternal pelvis is not of sufficient size and shape to allow passage of fetal head
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passenger
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ability of the fetus to move through the maternal pelvis is influenced by:
-diameter of the fetal skull- depends on degree of flexion and extension -position of the head - occiput relative to pelvis -molding: fetal head's ability to change shape |
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passive phase of 2nd stage
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from full dilatation until fetal head descends to pelvic floor
active phase: bearing down efforts of woman begins with each contraction |
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duration of 2nd stage
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30 mins to 3 hours - primi
5- 30 mins for multi |
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progress of second stage is protracted if:
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<1cm/hour nulli
<2cm/hr multi |
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progress of second stage is arrested if
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no descent in one hour in nulli
or 30 mins in multi |
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relationship between epidural analgesia and oxytocin
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normally increase of oxytocin in 2nd stage
this is blocked by epidural may need to start or increase oxytocin with epidural epidural can blunt maternal bearing down efforts |
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what is optimal postion for vaginal delivery
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Occiput anterior
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how can attendant enhance flexion or change postion
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manually, vacuum cup, forceps
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what is the main force driving fetus through birth canal
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propulsive force of uterine contractions
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mechanisms of labour
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in order to fit through maternal bony pelvis, the fetal head goes through changes in position as it passes through the birth canal
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name 6 mechanisms of labor
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descent
flexion internal rotation extension external rotation expulsion |
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descent
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occurs prior to onset of labor but greater rate in latter part of first stage and in 2nd stage
in 2nd stage- maternal bearing down also contributes other cardinal movements are superimposed on descent |
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flexion
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flexion of fetal head to chest, ecouraged by resistance of cervix, walls of the pelvis and pelvic floor
-optimizes presenting diameter to maternal pelvis |
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internal rotation
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fetal head enter pelvic inlet in transverse diameter
as fetal head contacts muscular sling of pelvic floor, it rotates so occiput is turned anteriorly to ward pubic symphsis= occiput anterior allows widest part of fetal head to move through birth canal at its area of widest dimension |
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extension
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vaginal outlet curves upward and forward, so to deliver, head must move from flexion to extension
caused by downward forces: uterine contractions, and maternal effort upward forces: pelvic floor muscles |
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crowning
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when the largest diameter of the baby's head is encircled by the vaginal opening-
occurs during extension |
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external rotation
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delivered head rotates back to the transverse position allows head to once again align with fetal shoulders and back
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expulsion
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anterior shoulder delivers first followed by posterior shoulder - then rest of body quickly delivers
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duration 3rd stage of labour
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average 5-10 mins
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signs of placental separation
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gush of blood from vagina
umbilical cord lengthening outside vagina fundus of uterus rises up into abdomen uterus becomes firm and globular |
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what period is the highest risk for post partum hemorrhage
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4th stage- especially first hour
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what is the most common cause of immediate post partum hemorrhage
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uterine atony- so assess tone of uterus regularly
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other causes of PPH
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retained tissues, coagulopathy, laceration of the perineum, vagina or cervix
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what is the classification for perineal lacerations?
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first degree- includes vaginal mucosa and perineal skin
second degree- extends into submucosal vagina, or perineum, may involve muscles perineal body third degree- involves anal sphincter forth degree- involves rectal mucosa |
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changes in uterus post partum
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contractions caused by oxytocin and PGF2A minimizes blood loss- after pains
uterus loses weight 1000g at delivery to 50-100 g at 4 weeks post partum |
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lochia
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is uterine discharge caused by sloughing off of decidual tissue, epithelial cells, bacteria and RBC
lochia rubra- red 3-4 days lochia serosa- becomes paler red/pink until 9-10 day lochia alba- yellowish white, contains more wbc starts at day 10 and continuous 4-8 weeks pp |
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cervix changes
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loses its elasticity and regains its prepregnancy firmness
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vaginal changes
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gradually regains its former tone but never returns to pre pregnant state
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changes in CV system post partum
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immediately after delivery- significant increase in peripheral vascular resistance due to removal of low-pressure uteroplacental circulation
cardiac output, HR and blood volume gradually decreases to normal in 2 weeks diuresis of extracellular fluid in first week pp results in 2-3 kg weight loss |
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breast changes
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intiation of lactation requires decrease of E and P from placenta - now prolactin can act
suckling stimulates release of prolactin and oxytocin |
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action of prolactin
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milk production
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oxytocin action
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causes contraction of myoepithelial cells in alveoli and milk ducts known as milk ejection reflex or let down
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colostrum
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deep lemon yellow liquid produced 2 days pp contains minerals, aa, proteins, and Ab (IgA) IT persists for 5 days with gradual conversion to mature milk
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what does mature milk contain
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fat proteins vitamins and Ab
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Postpartum blues
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transient state of heightened emotional reactivity lasting 2-3 days but can last up to 10 days
depression, anxiety, labile poor concentration and irritability |
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postpartum depression
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develops in 10-20% within 6 mo PP
caused by genetic and environmental can escalate depressive tendencies women who experience pp dep have a greater drop in estrogen and Progesterone pp |
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postpartum psychosis
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symptoms appear rapidly first two week pp
severely depressed moods, manic symptoms, disorganized thinking, delusions, hallucinations thoughts of suicide, infanticide - emergency |
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fetal hormonal changes in late pregnancy and early post partum period
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cortisol: increases few days prior to birth converting T4 to T3- necessary for neonatal thermogenesis
huge surge of TSH causes baby to by hyperthyroid for a few days to maintain body temp increase in catecholamines: responsible for mobilizing glucose, lung fluid absorption, alteration in perfusion of organ systems, and possibly onset of respiration |
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factors that influence the first breath
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physical stimulation during delivery
deprivation of O2 and accumulation of CO2, causing increased frequency and magnitude of breathing movements, compression of chest during birth- can force fluid from respiratory tract |
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transient tachypnea of the newborn
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delay in rapid replacement of bronchial and alveolar fluid by air
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what enables ductus arteriosus to close
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as fluid is replaced by air, compression of pulmonary vasculature, results in decreased resistance to pulmonary arterial blood flow and blood pressure enabling ductus arteriosus to close
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what does surfactant do
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synthesized in TII pneumocytes - lowers alveolar surface tension and prevents collapse of lung with each expiration
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