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80 Cards in this Set

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define cervical effacement
process by which uterine activity causes the cervix to be drawn intrabdominally into the lower uterine segment. it is also known as the thinnning or shortening of the cervix
labour
repetitive uterine contractions associated with progressive cervical effacement and dilatation
what is the length of human gestation
280 days
T or F a decrease in maternal progesterone is not seen at the onset of labor
t
role of PG in labor
PGE2, PGF2 alpha
PG is produced in the endometrium myometrium and chorioamnion
arachidonic acid, a precursor to PG is stored in cell membranes
labor triggers release of arachidonic acid and under the influence of COX is converted to PG
PGE2 role in cervix
PGE2 and relaxin induce changes in cervix associated with cervical repening
↑collagen lysis and ↑ wateraccumulation,
resultng in softening ↑ distensibility of the
cervix
PGF2 role in uterus
it is a potent stimulator for uterine contractions
-receptors for it are found in myometrial cell membrane and in sarcoplasmic reticulum
↑ in intracellular calcium as it is released from sarcoplasmic reticulum and from outside sources
high intracellular calcium enables the sliding of actin and myosin- allowing myometrial contractions
why are PGE2 analogues used
used as cervical repening agents
why are PG synthase inhibitors used
to stop preterm labor- tocolytic
Indomethacin
what is oxytocin
it is a prohormone stored in posterior pituitary
what happens to oxytocin receptors near term
increases
sensitivity of uterine muscles to oxtocin _____ near term
increases
low levels of oxytocin present throughout pregnancy but only increase significantly when __________
labor has begun
oxytocin release from the post pit is caused by various stimuli including:
distension of birth canal as baby moves through it
where does oxytocin bind
and what does it activate
oxytocin binds to oxytocin receptors on uterine muscle cell membrane
IP3 and DAG,
IP3 induces release of calcium from sarcoplasmic reticulum
why is synthetic oxytocin used
to enduce or augment labor
what does ethanol due to oxyocin release
inhibits it- tocolytic
oxytocin antagonis can be used as a ______
tocolytic
what are the 4 stages of labor
1st stage: time from onset of labor to full dilatation of the cervix
2nd stage: time from complete dilatation of the cervix to birth of the baby
3rd stage: time from birth of baby to delivery of placenta
4th stage: time from delivery of placenta to stabilization of patient- 6hrs postpartum
name 2 phases of the first stage of labor
latent phase,
active phase
Define latent phase: 1st stage
little appears to be happening
but contractions more coordinated, stronger and efficient
cervix softening, effacement, early dilatation, and movement from anterior to posterior
latent phase shorter in multiparous - 8 vs 5
define active phase 1st stage
begins when cervix is 3-4 cm dilated
dilatation occurs more rapidly
faster in multiparous 6 vs 3
duration of 1st stage
multi and nulli
6-18 nulli
2-10 for multi
what is extent of cervical effacement
2-3 cm to paper thin
measurement of progress of the delivery is by
cervical effacement, dilatation, consistency of the cervix, position of cervix and descent of fetal head
range of dilatation
1-10 cm
range of consistency
firm, medium, soft
range of cervical positions
in relation to vagina
posterior, midposition, anterior
descent of the fetal head
only occurs after full dilatation and in 2nd stage
once it begins it should be progressive
measure by stations
stations
relationship of presenting part of infant to an imaginary line between ischial spines
partogram
way to mark progress in dilatation and descent
3 PS OF MEASUREMENT OF PROGRESS
power passage and passenger
power - what can be done to improve it
if power of contraction is suboptimal can be improved by amniotomy if membranes are still intact
and oxytocin augmentation
passage
passage or shape of maternal pelvis cannot be altered
what are the 4 basic types of pelvis?
gynecoid
android
anthropoid
platypelloid
which two pelvis shapes are most conducive to labor
gynecoid and anthropoid
maternal obesity _______the likelihood of vaginal delivery
decreases
cephalopelvic disproportion
exists when maternal pelvis is not of sufficient size and shape to allow passage of fetal head
passenger
ability of the fetus to move through the maternal pelvis is influenced by:
-diameter of the fetal skull- depends on degree of flexion and extension
-position of the head - occiput relative to pelvis
-molding: fetal head's ability to change shape
passive phase of 2nd stage
from full dilatation until fetal head descends to pelvic floor
active phase: bearing down efforts of woman begins with each contraction
duration of 2nd stage
30 mins to 3 hours - primi
5- 30 mins for multi
progress of second stage is protracted if:
<1cm/hour nulli
<2cm/hr multi
progress of second stage is arrested if
no descent in one hour in nulli
or 30 mins in multi
relationship between epidural analgesia and oxytocin
normally increase of oxytocin in 2nd stage
this is blocked by epidural
may need to start or increase oxytocin with epidural
epidural can blunt maternal bearing down efforts
what is optimal postion for vaginal delivery
Occiput anterior
how can attendant enhance flexion or change postion
manually, vacuum cup, forceps
what is the main force driving fetus through birth canal
propulsive force of uterine contractions
mechanisms of labour
in order to fit through maternal bony pelvis, the fetal head goes through changes in position as it passes through the birth canal
name 6 mechanisms of labor
descent
flexion
internal rotation
extension
external rotation
expulsion
descent
occurs prior to onset of labor but greater rate in latter part of first stage and in 2nd stage
in 2nd stage- maternal bearing down also contributes
other cardinal movements are superimposed on descent
flexion
flexion of fetal head to chest, ecouraged by resistance of cervix, walls of the pelvis and pelvic floor
-optimizes presenting diameter to maternal pelvis
internal rotation
fetal head enter pelvic inlet in transverse diameter
as fetal head contacts muscular sling of pelvic floor, it rotates so occiput is turned anteriorly to ward pubic symphsis= occiput anterior
allows widest part of fetal head to move through birth canal at its area of widest dimension
extension
vaginal outlet curves upward and forward, so to deliver, head must move from flexion to extension
caused by downward forces: uterine contractions, and maternal effort
upward forces: pelvic floor muscles
crowning
when the largest diameter of the baby's head is encircled by the vaginal opening-
occurs during extension
external rotation
delivered head rotates back to the transverse position allows head to once again align with fetal shoulders and back
expulsion
anterior shoulder delivers first followed by posterior shoulder - then rest of body quickly delivers
duration 3rd stage of labour
average 5-10 mins
signs of placental separation
gush of blood from vagina
umbilical cord lengthening outside vagina
fundus of uterus rises up into abdomen
uterus becomes firm and globular
what period is the highest risk for post partum hemorrhage
4th stage- especially first hour
what is the most common cause of immediate post partum hemorrhage
uterine atony- so assess tone of uterus regularly
other causes of PPH
retained tissues, coagulopathy, laceration of the perineum, vagina or cervix
what is the classification for perineal lacerations?
first degree- includes vaginal mucosa and perineal skin
second degree- extends into submucosal vagina, or perineum, may involve muscles perineal body
third degree- involves anal sphincter
forth degree- involves rectal mucosa
changes in uterus post partum
contractions caused by oxytocin and PGF2A minimizes blood loss- after pains
uterus loses weight 1000g at delivery to 50-100 g at 4 weeks post partum
lochia
is uterine discharge caused by sloughing off of decidual tissue, epithelial cells, bacteria and RBC
lochia rubra- red 3-4 days
lochia serosa- becomes paler red/pink until 9-10 day
lochia alba- yellowish white, contains more wbc starts at day 10 and continuous 4-8 weeks pp
cervix changes
loses its elasticity and regains its prepregnancy firmness
vaginal changes
gradually regains its former tone but never returns to pre pregnant state
changes in CV system post partum
immediately after delivery- significant increase in peripheral vascular resistance due to removal of low-pressure uteroplacental circulation
cardiac output, HR and blood volume gradually decreases to normal in 2 weeks
diuresis of extracellular fluid in first week pp results in 2-3 kg weight loss
breast changes
intiation of lactation requires decrease of E and P from placenta - now prolactin can act
suckling stimulates release of prolactin and oxytocin
action of prolactin
milk production
oxytocin action
causes contraction of myoepithelial cells in alveoli and milk ducts known as milk ejection reflex or let down
colostrum
deep lemon yellow liquid produced 2 days pp contains minerals, aa, proteins, and Ab (IgA) IT persists for 5 days with gradual conversion to mature milk
what does mature milk contain
fat proteins vitamins and Ab
Postpartum blues
transient state of heightened emotional reactivity lasting 2-3 days but can last up to 10 days
depression, anxiety, labile poor concentration and irritability
postpartum depression
develops in 10-20% within 6 mo PP
caused by genetic and environmental
can escalate depressive tendencies
women who experience pp dep have a greater drop in estrogen and Progesterone pp
postpartum psychosis
symptoms appear rapidly first two week pp
severely depressed moods, manic symptoms, disorganized thinking, delusions, hallucinations
thoughts of suicide, infanticide - emergency
fetal hormonal changes in late pregnancy and early post partum period
cortisol: increases few days prior to birth converting T4 to T3- necessary for neonatal thermogenesis
huge surge of TSH causes baby to by hyperthyroid for a few days to maintain body temp
increase in catecholamines: responsible for mobilizing glucose, lung fluid absorption, alteration in perfusion of organ systems, and possibly onset of respiration
factors that influence the first breath
physical stimulation during delivery
deprivation of O2 and accumulation of CO2, causing increased frequency and magnitude of breathing movements,
compression of chest during birth- can force fluid from respiratory tract
transient tachypnea of the newborn
delay in rapid replacement of bronchial and alveolar fluid by air
what enables ductus arteriosus to close
as fluid is replaced by air, compression of pulmonary vasculature, results in decreased resistance to pulmonary arterial blood flow and blood pressure enabling ductus arteriosus to close
what does surfactant do
synthesized in TII pneumocytes - lowers alveolar surface tension and prevents collapse of lung with each expiration