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8 Cards in this Set

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nigrostriatal pathway
grp of neurons projecting from substantia nigra to striatum
90% of dopamine in brain produced in...
..substantia nigra
6-OHDA
6-hydroxydopamine

kill dopamine neurons w/o harming surroudng tissues
catecholamines
dop
epin
norepin
MAO
monoamine oxidase

breaks down dopamine
DMI
desmethylimipramine

blocks uptake transporter proteins located on norepinephrine and epinephrine neurons
MPTP
methyl-phenyl-tetrahydrophyridine
MPP+
methyl phenylpyridinium

selectively kills dopaminergic cells of substantia nigra