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22 Cards in this Set

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a. Short half-life. Pick up changes in protein status quickly.


b. During inflammation, liver synthesized CRP at expense of PAB


c. limited usefulness in screening or assessment.

TTHY Transthyretin, PAB Prealbumin

a. Circulates with pre-albumin. Shortness half-life (12 hrs)


b. Binds and transports retinol

RBP Retinol-binding protein 3-6 mg/dL

Volume of packed cells in whole blood.

Hematocrit


Men 42-52%


Women 36-48%


Pregnant women 33%


Newborn 44-64%

Hct

a. Iron-containing pigment of red blood cells


b. Erythrocytes are produced in bone marrow

Hemoglobin


Men 14-18 gm/dL


Women 12-16 gm/dL


Pregnant > 11

Hgb

a. indicates size of iron storage pool.

10-150 ng/ml


F 12-300 ng/ml M


Serum ferritin

a. Related to muscle mass; measures somatic protein


b. May indicate renal disease, muscle wastage

Serum Creatinine


0.6-1.2 mg/dL

a. Ratio of creatinine excreted/ 24 hours to height


b. estimates lean body mass - somatic protein


C. 60-80% mild muscle depletion

Creatinine height index

CHI

a. related to protein intake


b. indicator of renal disease


Blood urea nitrogen 10-20 mg/dL


c. BUN: creatinine ratio normal 10-15:1

BUN

a. Measures GFR - glomerular filtration, renal function


b. estimate includes body surface area (height and weight)

Urinary creatinine clearance


115 +/- 20 ml/minute

a. measure immunocompetency


b. moderate depletion 900-1800, severe depletion <900


c. decrease in protein-energy malnutrition

Total lymphocyte count >2700 cells/cu mm

TLC

a. as ______ declines, indicates when nutritional therapy would be beneficial


b. when PAB increases, ______ decreases

C-Reactive Protein

CRP

Direct measure of toxic effects of lead on gene synthesis. Increased in lead poisoning. Lead depleted iron leading to anemia.

Free erythrocyte protoporphyrin

FEP

a. anticoagulants prolong PT


b. evaluates clotting adequacy; change in Vitamin K intake will alter rate

Prothrombin time

PT

Not for Nutritional assessment; useful in measuring intake of toxic metals

Hair analysis

Based on activity factors and BEE

BEE x 1.2 Sedentary


BEE x 1.3 Active


BEE x 1.5 stressed

Assessment of energy requirements

Depletes pyridoxine, peripheral neuropathy, don’t take with food, interferes with Vitamin D, Calcium, phosphorus

Isoniazid

Treats TB

Sedative effect, weight gain, increased appetite

Elavil (antidepressant)

Decrease effectiveness of


L-dopa (levodopa) which controls symptoms of Parkinson’s disease. Take drug in morning with limited protein (competes with drug for absorption sites)

Vitamin B6 and Protein

Binds tetracycline

Calcium

Hypertension if taken with MAOI (monoamine oxidase inhibitor)

Tyramine

Tyramine avoid and ok lists

Mechanism


1. Eliminate dopamine and restrict tyramine (monoamines). MAO inhibitors interact releasing norephribe which elevated blood pressure. Restrict aged, fermented, dried, pickled, smoked, spoiled foods.


2. Avoid hard, aged cheese (cheddar, Swiss), sauerkraut, some sausages, luncheon meats, tofu, miso, chianti wine. Limit sour cream, yogurt, buttermilk.


3. Ok: cottage cheese, cream cheese, good advice: buy, cook, eat fresh foods.

May reduce inflammation, antioxidant, in curry powder

Turmeric