Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
39 Cards in this Set
- Front
- Back
|
All connective tissues consist of:
|
Cells + ECM
|
|
|
ECM consists of
|
Fibers + Ground substance
|
|
|
Ground substance consists of:
|
-Proteoglycans
-Glycoproteins -GAGs |
|
|
What are the cells in cartilage?
|
Chondrocytes
|
|
|
3 types of cartilage:
|
-Hyaline
-Elastic -Fibrocartilage |
|
|
What is the pink staining material at the periphery of the hyaline cartilage in a trachea?
|
Perichondrium
|
|
|
What cells are in the perichondrium?
|
Chondrogenic cells
|
|
|
What do Chondrogenic cells become? How?
|
Chondroblasts - by enlarging
|
|
|
What do chondroblasts do?
|
Grow and secrete ECM
|
|
|
What do Chondroblsts become when surrounded by cartilage?
|
Chondrocytes
|
|
|
Function of chondrocytes:
|
Secrete and maintain the ECM of cartilage.
|
|
|
Prominent organelles in chondrocytes:
|
-rough ER
-Golgi |
|
|
What the rough ER and golgi secrete:
|
-Collagen
-Elastin -Ground substance |
|
|
What is it called when chondrogenic cells become chondroblasts and make new cartilage?
|
Appositional - from without
|
|
|
General appearance of hyaline cartilage:
|
homogenous
|
|
|
Type of collagen in hyaline cartilage:
|
Type II
|
|
|
Where are the largest chondrocytes in the trachea ring?
|
In the center - the oldest
|
|
|
What spaces do chondrocytes occupy?
|
Lacunae
|
|
|
What are the small clones of cells that chondrocytes in young cartilage create called?
|
Cell nests
|
|
|
What happens to these cell nests?
|
The chondrocytes secrete ECM and separate - enlarging the cartilage.
|
|
|
What is it called when cartilage grows from within cell nests?
|
Interstitial growth
|
|
|
What makes territorial matrix different from interterritorial?
|
More basophilic due to higher negative charge of more proteoglycans, less collagen
|
|
|
Type of collagen in Hyaline cartilage:
|
Type II
|
|
|
Type of collagen in Elastic cartilage:
|
Type II
|
|
|
Type of collagen in Fibrocartilage:
|
Type I
|
|
|
Why are collagen fibers undistinguishable within the ECM of hyaline and elastic cartilage?
|
Because Type II collagen fibers are much smaller than type I
|
|
|
What other type of cartilage is elastic cartilage most similar to?
|
Hyaline
|
|
|
How does elastic cartilage compare to hyaline macroscopically?
|
Stringier - Heterogenous
Hyaline is homogenous |
|
|
Where is elastic cartilage in the body?
|
-Auricle
-External auditory canal -Eustachian tube -Epiglottis |
|
|
What type of collagen is in fibrocartilage?
|
Type I
|
|
|
Does fibrocartilage have a perichondrium?
|
no
|
|
|
What is unique about the condrocytes in fibrocartilage?
|
They are surrounded by very little matrix.
|
|
|
What is the macroscopic appearance of fibrocartilage like?
|
Herringbone
|
|
|
Why is fibrocartilage arranged the way it is?
|
To resist both compressive and sheer forces and help it act as a shock absorber.
|
|
|
How are the chondrocytes in fibrocartilage arranged?
|
In parallel rows between layers of collagen bundles.
|
|
|
What type of cartilage covers bone surfaces at synovial joints?
|
Articular - a subdivision of hyaline
|
|
|
Does articular cartilage have a perichondrium?
|
no
|
|
|
What is the purpose of lacking a perichondrium?
|
To make the surface smoother and allow for low friction gliding of the surfaces that articulate.
|
|
|
Compared to mature cartilage how much cells and matrix is in developing cartilage?
|
-More cells
-Less matrix |
