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28 Cards in this Set

  • Front
  • Back
2 main types of bone based on macroscopic appearance:
-spongy
-compact
Are spongy and compact bone different microscopically?
no
2 types of microscopically different bone:
-Woven (immature)
-Lamellar (mature)
What makes woven bone woven?
The fact that collagen fibers within it are NOT parallel and organized.
Why is lamellar bone better?
Because collagen fibers are parallel and organized, so much stronger.
What are the systems made up by concentric layers of lamellae in compact bone called?
Haversian systems
Another name for a Haversian system?
Osteon
What occupies the gaps between osteons?
Interstitial lamellae
What is at the center of each osteon?
Haversian canal
What is present in the haversian canal in living bone?
-Blood vessels
-Nerves
-Osteoblasts/osteoprogenitors
What are the layers of bone that surround the haversian canal?
Concentric Lamellae
What are the spaces between lamellae called?
Lacunae
What is housed within lacunae?
Osteocytes
What are the tiny dark lines that radiate from each lacuna?
Canaliculi
What is the function of canaliculi?
To allow for diffusion of metabolites between bl vessels and adjacent osteocytes via gap junctions.
What are interstitial lamellae?
Remnants of older osteons that have been partially resorbed.
What are the canals that are oriented perpendicular to haversian canals called?
Volkmann's Perforating canals
What does spongy bone have?
Trabeculae
What is another word for trabeculae?
Spicules
What are trabeculae?
Projections of spongy bone cut in various directions.
What small cells can be found between trabeculae in spongy bone?
Red bone marrow cells
By what type of process does bone grow in girth?
Appositional
What are chondroclasts?
Multinucleated cells that eat up cartilage as it is replaced by bone during endochondral ossification.
Are chondroclasts different from osteoclasts? Where would you find them?
Only in terms of what they break down.
-Found in calcification and ossification zones of the epiphyseal plate.
What are the 5 zones of the epiphyseal plate?
1. Reserve zone
2. Proliferative zone
3. Hypertrophy zone
4. Calcification zone
5. Ossification zone
What has cell nests, cartilage or bone?
Cartilage
Which has blood vessels within the matrix, cartilage or bone?
Neither
Which has lamellae?
Bone