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16 Cards in this Set
- Front
- Back
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Antibiotic |
Substance produced by living organism that inhibits survival of another |
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Antibiosis |
Process of an organism producing an antibiotic |
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Most common antibiotic producers |
Bacillus and streptomyces |
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Alexander Fleming |
Penicillin from penicillium |
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Antibiotic mechanisms |
Inhibit plasma membrane function, cell wall synthesis, protein synthesis, metabolic pathways, nucleic acid synthesis |
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VRE |
Vancomycin Resistant Enteroccocus |
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CRE |
Carbapenum Resistant Enterobacteriaceae |
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MIC |
Minimal Inhibitory Concentration Lowest conc. of antibiotic that will inhibit bacterial growth |
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MBC |
Minimal Bacteriocidal Concentration Lowest conc. of antibiotic that will kill bacteria |
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Kirby-Bauer Susceptibility Test |
Standard by which all antibiotics are tested, standard in all countries |
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Standard concentration |
0.5 McFarland 1 hundred million org/mL |
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Standard media |
Mueller Hinton media 4mm thickness pH 7.2-7.4 |
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Standard antibiotic disc size |
6mm Taxo A Bacatracin 0.04 units NB5 Novobiocin 5 micrograms |
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Standard incubation time + temp |
35 +- 2°C read after 18-24 hours |
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Intermediate Resistant |
Organisms may or may not be inhibited/killed by antibiotic Higher dose may work |
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Broad Spectrum Antibiotics |
CIP5 + GM10 |
