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74 Cards in this Set

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What four tests does urinalysis test to detect and assess?
Renal function/disorder
Endocrine or metobolic function disorder
Urinary tract infection
Systemic disease
What are the clinical reasons for performing a urinalysis?
Importnat indicator of health, cost effective in-vitro diagnostic test, non invasive procedure and simple to perform
What are the two methods of urine collection?
Non-instrumented
Instrumented
What are the four non-instrumented methods of urine collection?
First morning void
Random urine specimen
Clean catch
24 hour urine
What are the four instrumented methods of urine collection?
Urethral Catherization
Suprapubic needle aspiration
Catheterization and bladder irrigation
After collection when is urine preffered to be analyzed?
1-2 hours
How long can the urine specimen be refregierated if unable to test immediately?
3-6 hours
What are the 3 mechanisms of urine decomposition?
Presence of bacteria in sample
Urea splitting bacteria
Changes in sample
What will increase the pH in a urine sample?
Urea splitting bacteria produces ammonia and combines with hydrogen ions
What results if pH level is increased in urine?
It will dissolve any casts present
What will glucose in a sample do?
Create a false negative for glycosuria
What does a urine sample need to prevent deterioration of blood cells and casts?
Preservatives
What does using preservatives in urine specimen enable?
Transport of urine from home to lab
Shipment of urine across country
Which preservative method is used for transport but may destroy formed elements?
Freezing
Which preservative method preserves acetone, diacetic acid and proteins by floating on the top of the urine but is hard to seperate?
Toluene
Which preservatives inhibits bacteria/fungus yet gives a false positive for protein?
Thymol
Which preservative preserves urine aldosterone levels but settles to the bottom of containers?
Chloroform
What preserves urinary sediment/cells but interferes with glucose elevation?
Formaldehyde
What stabilizes steroids and is a hazardous liquid with fumes and destroys formed elements in the urine?
Hydrogen Chloride
Preserves chemical and formed elements but may precipitate uric acid
Boric Acid
Preserves urine for dipstick chemical analysis and sediment evaluation but is unsuitable for sodium, potassium, and hormone analysis
Preservative tablet
Which collection is the most concentrated and is the recommended specimen for chemical and microscopic examinations?
First morning void
which collection method is the most common and can be taken at any time?
Random urine sample
Which collection method is the choice for bacterial cultures and can have cultures performed if refrigerated within 12 hours of collection?
Clean catch
Which specimen gives quatitative results and may need preservatives?
24-hour urine
Which collection method is not recommended for bacteriological exam and is to be used only if there is no other way and on obese patients?
Urethral Catherization
Which collection method is the choice for infants and very young children?
Suprapubic needle aspiration
Which collection method involves inserting 50-72 mL saline and then removed for cytology study?
Catherization and bladder irrigation
What are the three urine sample analysis?
Physical
Chemical
Microscope
What is the normal urine volume in a 24 hour period?
600-2000 mL
What is the average volume of urine in a 24 hour period?
1500 mL
What is urine amount directly related to?
Fluid intake
Temperature and Climate
Amount of persperation
What is the normal color of urine?
Yellow to dark amber
What is the significance of blue green urine?
Methylene blue (used as dye or stain)
Dark orange urine
Pyridium
Milky white urine
Chyle
Olive Green to brown black urine
Phenols (poisenous compound used for antimicrobial agent)
Yellow to brown urine
(turns greenish with foam when shaken) Presence of bile
red or red brown (smoky) urine
presence of blood
What is turbid alkaline urine due to?
Amorphous phosphate
Amorphous carbonate
What is turbid acidic urine due to?
Amorphous urates
What does the pinkish turbidity frequently indicate?
Presence of urates
What is not considered to be of diagnostc importance?
Odor
When urine has been standing for a long time what odor developes?
Ammonia
If urine has a sweet fruity smell what does that indicate?
Keytones
If urine has a pungent smell what does that indicate?
Ammonia produced by bacteria
Urine with a maple syrup odor indicates
Maple syrup urine disease a congenital metabolic disorder
If urine is musty or mousy odor
infant with phenylketonuria
If urine has a sweaty feet odor
Isovaleric academia, presence of butyric or hexanoic acid
What is the specific gravity for random urine
1.003-1.035
What is the specific gravity for 24 hour urine?
1.015-1.025
What is the quantity of glucose in urine dependant on?
Blood glucose level
What is the threshold level of glucose in urine?
160-180 mg/dL
Glucosuria may indicate what?
Diabetes Mellitus
Keytones in the urine indicate?
Incomplete utilization of fatty acid
What conditions are associated with keytonuria?
Decrease intake of carbs(starvation)
Decrease utilization of carbs (diabetes Mellitus)
Dietary imbalance (high fat low carb)
Eclampsia
Prolongued vomiting and diarrhea
What is presence of blood in the urine known as?
Hematuria
What do RBC's in the urine indicate?
Damage or trauma to the kidney or urinary tract
Renal disease
What condition is caused by bilirubin in the system
Jaundice
What color is urine containing bilirubins
Brown to black(amber)
What does bilirubinuria indicate?
Hepatocellular disease
Intra or extra hepatic biliary obstruction
What is normally present in the urine at a a concentration of 1 EU or less?
Urobilinogen
What is the normal amount of urobilinogen?
1mg/dL
What are the normal pH ranges for urine?
4.6-8.0
What is the average pH level in urine?
6.0
What pathologic conditions may cause acidic urine?
Respiratpry and metabolic acidosis
UTI
Uremia
Severe Diarrhea
Starvation

What are some pathologic conditions that cause alkaline urine?
UTI's caused by proteus and psuedomonos species
Respiratory and metabolic alkalosis
What is protein in the urine an indicator of?
Renal disease
What two mechanisms do proteinuria occur in?
Glomerular damage and defect in the reabsorbsion process of the tubules
What are the values for minimal proteinuria?
<0.5 g/day
What are disease attached to minimal proteinuria
Polycystic kidneys
Chronic pyelonephritis
Inactive chronic glomerulonephritis
benign orthostatic proteinuria
What are the values for moderate proteinuria?
0.5-3.5g/day
What are the values for severe proteinuria?
>3.5 g/day
What is an indirect test for bacteria?
Leukocyte esterase