Kobgyn 850-900

Front 1

Q850. MC cancer of the vagina

Back 1

A850. SCC: 85% (Clear cell is with DES exposure: 5%)

Front 2

Q851. How is Vaginal SCC Tx with each stage (I-IV)?

Back 2

A851. Stage I and II: Surgical excision; Stage III and IV: Radiation therapy

Front 3

Q852. where does CIN usually begin and where is it most likely to be growing?

Back 3

A852. starts: Transformation zone of cervix; MC place: Anterior lip of cervix

Front 4

Q853. what are the (4) HPV types that are high-risk types for CIN and CA?

Back 4

A853. 16, 18, 31, 45

Front 5

Q854. at what age is CIN most commonly Dx?; by what percent can Pap smears reduce the incidence?

Back 5

A854. women in their 20's; Paps reduce incidence by 90%

Front 6

Q855. if woman has a hysterectomy for a benign condition like fibroids, how often should they have a pap smear?

Back 6

A855. they do not need to continue regular paps; (they do if their cervix is intact)

Front 7

Q856. current recommendations of time to begin Pap smears

Back 7

A856. within 3 years of becoming sexually active or by age 21

Front 8

Q857. what percent of women have Atypical Squamous Cell Pap smears that harbor severe dysplasia histology?

Back 8

A857. 10 - 15%

Front 9

Q858. what is the next step in Tx for pap smears that come back as:; ASC-US (unknown significance); ASC-H (cannot rule-out High grade)

Back 9

A858. ASC-US: HPV testing (HPV negative: regular Paps) (HPV positive: Colposcopy with biopsy); ASC-H: Colposcopy with biopsy

Front 10

Q859. what is the management of Tx if patient has ASC-US, High risk HPV negative?

Back 10

A859. repeat Pap smear and HPV testing in one year

Front 11

Q860. what is the management of Tx if patient has CIN-I versus CIN-II and CIN-III?

Back 11

A860. CIN-I: repeat Pap every 6 mo for 1 year; if still has CIN-I, do LEEP; CIN-II and CIN-III: LEEP

Front 12

Q861. Complications of LEEP; (4)

Back 12

A861. Cervical Stenosis,; Cervical Incompetence,; Infection,; Bleeding

Front 13

Q862. what is management if patient has CIN that is a large lesion, in a teenage patient or involves the vagina?

Back 13

A862. Laser Ablation

Front 14

Q863. what is the Tx for Preinvasive (stage 0) or microinvasive; (stage Ia-1) cervical cancer?; (2 possible)

Back 14

A863. Cone biopsy,; Simple Hysterectomy

Front 15

Q864. what is the Tx for Stage IIb - IV cervical CA?; (2)

Back 15

A864. Chemotherapy (Cisplatin); and Radiation (ONLY)

Front 16

Q865. what is the Tx for Stage Ia-2 to IIa cervical CA?; (2 possibilities)

Back 16

A865. Radical Hysterectomy; or External Radiation

Front 17

Q866. what is the difference b/t the presentation of:; Mastitis,; Blocked duct,; Mammary Ectasia,; Engorgement

Back 17

A866. Mastitis: Unilateral and fever; Blocked duct: Unilateral, no fever; Mammary Ectasia: Bilateral, green discharge; Engorgement: Bilateral during preg

Front 18

Q867. what is the 5-year survival rate for cervical CA stage I?; stage IV?

Back 18

A867. Stage I: 85 - 90%; Stage IV: 15 - 20%

Front 19

Q868. MC GYN cancer in USA

Back 19

A868. Endometrial CA

Front 20

Q869. MC type of endometrial CA; what is the average age to Dx endometrial CA?

Back 20

A869. Endometrioid AdenoCA; Ave age: 61

Front 21

Q870. what is the Tx for endometrial CA for stages:; 1. I and II; 2. III and IV

Back 21

A870. I and II: TAHBSO, then radiation; III and IV: TAHBSO and Para-aortic LN removal, then radiation

Front 22

Q871. what is the Tx for recurrent endometrial CA?; when does recurrence usually occur?

Back 22

A871. High-dose Progestins; recurrence: 85% occur w/i 3 years

Front 23

Q872. how common is Ovarian CA compared to all GYN cancers?; what percent of deaths from cancer of the female gential tract?

Back 23

A872. 25% of all GYN cancers; responsible for 50% of GYN deaths; (b/c of lack of screening tools)

Front 24

Q873. MC place on ovary where cancers form

Back 24

A873. Epithelium on ovary capsule; (Coelomic epithelium)

Front 25

Q874. what is a common familial cancer syndrome that also is seen to include ovarian cancer?

Back 25

A874. Lynch II syndrome; (Hereditary nonpolyposis Colorectal CA)

Front 26

Q875. what is the chance a woman will get ovarian cancer?

Back 26

A875. 1 in 60

Front 27

Q876. Dx:; ovarian cancer that mets to umbilicus

Back 27

A876. Sister Mary Joseph nodule

Front 28

Q877. what is the tumor marker in 80% of epithelial ovarian tumors?; at what stage are most diagnosed?

Back 28

A877. CA-125; most Dx at Stage III

Front 29

Q878. Ovarian tumor type:; asymptomatic, with possible low abdominal discomfort and early satiety

Back 29

A878. Ovarian Epithelial tumor

Front 30

Q879. what is the 5-year survival rate for Epithelial Ovarian CA?

Back 30

A879. 0.2

Front 31

Q880. Tx for Epithelial Ovarian CA; (procedure and 2 drugs)

Back 31

A880. TAHBSO,; followed by: Taxol and Carboplatin chemo

Front 32

Q881. (2) of the MC types of Germ cell tumors

Back 32

A881. Dysgerminomas; Immature Teratomas

Front 33

Q882. Dx:; ovarian tumor with cancer markers of CA-125 and LDH

Back 33

A882. Dysgerminoma

Front 34

Q883. what is the only thyroid or parathyroid hormone that crosses the placenta?

Back 34

A883. TSH

Front 35

Q884. germ cell ovarian tumors are most commonly seen in what population?

Back 35

A884. women < 20 yo

Front 36

Q885. Tx for Germ cell tumors; (procedure and 3 drugs)

Back 36

A885. Unilateral Saplingo-oophorectomy; drugs (BEP): Bleomycin, Etoposide, CisPlatin [med for GERM: BE Penicillin]

Front 37

Q886. MC age for all Sex-cord tumors except Sertoli-Leygig. what is age for Sertoli-Leydig?

Back 37

A886. 40 - 70 yo; S-L: < 40 yo

Front 38

Q887. MC type of Sex-cord tumor

Back 38

A887. Granulosa cell tumor (70%)

Front 39

Q888. Dx:; ovarian tumor that secretes Inhibin and Estrogen; (causing feminization)

Back 39

A888. Granulosa-Theca cell tumor

Front 40

Q889. Dx:; ovarian tumor that secretes Androgens (causing virilization)

Back 40

A889. Sertoli-Leydig cell tumors

Front 41

Q890. what causes the nonfunctioning tumor: Ovarian Fibroma?

Back 41

A890. mature fibroblasts

Front 42

Q891. Dx:; Ovarian tumor, ascites, right hydrothorax

Back 42

A891. Meig's syndrome

Front 43

Q892. what sex cord-stromal ovarian tumor can recur 15 to 20 years later?

Back 43

A892. Granulosa cell tumors

Front 44

Q893. Tx for sex cord-stromal tumors in young patients?; old patients?

Back 44

A893. young: Unilateral Salpingo-Oophorectomy; older: TAHBSO; (never chemo or radiation)

Front 45

Q894. MC type of fallopian tube cancers

Back 45

A894. Adenocarcinoma (from mucosa)

Front 46

Q895. Dx:; abdominal pain, profuse watery discharge from vagina, pelvic mass

Back 46

A895. Fallopian tube CA

Front 47

Q896. Tx for fallopian tube CA; (procedure and 2 drugs)

Back 47

A896. TAHBSO,; drugs: Taxol, Carboplatin

Front 48

Q897. Definition:; intermittent hydrosalpinx; what is it seen in?

Back 48

A897. Hydrops tubae profluens; (seen in fallopian tube CA)

Front 49

Q898. Definition:; fertilization of an egg without a nucleus by one sperm

Back 49

A898. Complete Mole

Front 50

Q899. who do the chromosomes come from in a Complete mole?; what is most common karyotype?

Back 50

A899. Paternal; 46,XX

Front 51

Q900. Dx:; irregular or heavy bleeding during early pregnancy, hyperemesis gravidarum, preeclampsia, hyperthyroidism, large uterine size, b-hCG > 50,000

Back 51

A900. Complete mole