Kn: Lympathics & Immunity

Front 1

3 functions of lympathic system?

Back 1

fluid balance
absorb fats
defense system

Front 2

What are the lympatic organs? 7

Back 2

lymph tissue
nodules
tonsils
nodes
spleen
thymus
lymph vessels

Front 3

What do lymph tissue consist of & where is it usually found?

Back 3

contains mucus membranes
-contained in area open to external environment

Front 4

Function of Spleen?

Back 4

destroy foreign substances like old rbc

Front 5

Lympathic tissue in spleen?

Back 5

pulp

Front 6

Where are lymphocytes produced in Thymus?

Back 6

cortex

Front 7

Role of medulla in Thymus?

Back 7

regulatory T-cell maturation

Front 8

What hormomes does the medulla of the Thymus secrete for T-cell maturation? 2

Back 8

Thymosin
thymopoietin

Front 9

Where do lymph vessels enter?

Back 9

venous system

Front 10

2 parts of immune system?

Back 10

Innate/Non-specific Resistance
Adaptive/Specific Resistance

Front 11

Innate Resistance: mechanical barriers? 4

Back 11

skin
mucus
saliva
tears

Front 12

Innate Resistance: Chemicals? 6

Back 12

enzymes
acids
histamine
prostaglandins
leukotrienes
leukocyte inducing factors

Front 13

Innate Resistance: what are cells? function?

Back 13

Leukocytes
kill by lysosomal degradation and proteasomes

Front 14

Types of Leukocytes? 5

Back 14

neutrophils
macrophages
basophil
mast cell
natural killer cells

Front 15

Function of Neurophils?

Back 15

phagocytic and then die to form pus

Front 16

Function of Macrophage?

Back 16

very phagocytic

Front 17

Function of Basophils? 2

Back 17

release histamine for vasodilation
release leukotrienes to attract other cells

Front 18

Function of Mast cell?

Back 18

release histamine, heparin

Front 19

Function of Natural Killer cells?

Back 19

kill tumor and virus cells by chemical lysis

Front 20

Innate Resistance: Antimicrobial Proteins?

Back 20

complement
interferon

Front 21

What do Interferon proteins respond too?

Back 21

viral infections

Front 22

What activates complement proteins?

Back 22

cell wall/membrane of micro organism

Front 23

Membrane Attack Complex (MAC)?

Back 23

complement proteins group together to form this large protein complex

Front 24

Function of MAC?

Back 24

bind to cell membranes of invading organism and create a opening in microorganism membrane
-this causes lysis of cell and opsonization for white cells

Front 25

Adaptive Resistance: Characteristics? 3

Back 25

recognition
systemic
memory

Front 26

Adaptive Resistance: role of antigens?

Back 26

stimulate immune system

Front 27

Types of antigens? 2

Back 27

foreign
self

Front 28

What are foreign antigens?

Back 28

bacteria
viruses

Front 29

Role of MHC (Major histocompatibility protein)?

Back 29

tells other cells of the immune system that something is healthy to prevent a immune response

Front 30

Autoimmune?

Back 30

malfunctioning of self recognition
-attack out own cells

Front 31

Adaptive Resistance: Cells & Proteins?

Back 31

lymphocytes
antigen presenting cells
complement proteins

Front 32

2 types of Lymphocytes?

Back 32

B cells
T cells

Front 33

Role of B cells?

Back 33

produce antibodies

Front 34

Types of T-cells and their role?

Back 34

cytotoxic T cells- CD8 kill directly
helper T cells-CD4 assist other white cells
regulatory T cell- dampen immune response and help prevent auto immune diseases

Front 35

Types of Antigen Presenting cells? 4

Back 35

macrophages
dendritic cells
langerhans cells
B-lymphocytes

Front 36

Constant & variable regions of Antibodies?

Back 36

constant- class
variable- antigen binding site

Front 37

Active Humoral immunity? 2

Back 37

memory cells from previous infection
vaccine-receive inactive antigen

Front 38

Passive Humoral Immunity?

Back 38

pregnancy

Front 39

What happens after T cell is activated?

Back 39

T cells proliferate as a clone