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21 Cards in this Set
- Front
- Back
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What happens when a blood vessel tears? 3
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vessels constricts
platelets clump coagulation of proteins form a clot |
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How does Hemostasis stop blood flow? 3
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vascular spasm
platelet plug formation coagulation |
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Vascular spasm?
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short contraction of smooth muscle in the vessel
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What is released when Platelet plug formation occurs? 4
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Thromboxane
ADP Serotonin Platelet Factor 3 |
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Thromoboxane? 2
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spasms
platelet adherance |
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ADP?
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platelet adherence
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Serotonin?
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spasm of blood vessels
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Platelet factor 3?
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external clotting mechanism
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When does Platelet formation occur?
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a small tear in blood vessel
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When does coagulation occur?
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a large tear in blood vessel
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Where are clotting factors found?
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liver
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Where are factors for coagulation found?
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plasma
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3 steps in coagulation cascade?
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-production of prothrombin activator
-conversion of prothrombin to thrombin -Fibrinogen converted to fibrin |
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Anticoagulation? 2
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control of coagulation
focuses on removal of thrombin |
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Role of Prostacyclin?
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decreases platelet aggregation
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What does a mature clot consist of? 4
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blood cells trapped
platelets have aggregated fibrin threads woven throughout attached to wall of blood vessel |
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What happens during clot retraction and dissolution?
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vessel contracts to squeeze out serum
-this pulls edges together -PDGF rebuild the wall of blood vessel |
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Fibrinolysis?
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breaks down fibrin clot
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What hormone is responsible for Fibrinolysis and what activates it?
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Plasminogen
-activated by several factors including thrombin |
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Location of Antigens?
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proteins on surface on cell
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What steps are done for diagnostic blood test? 4
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-type and crossmatch
-complete blood count -clotting factors -blood chemistry |
