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13 Cards in this Set
- Front
- Back
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What is considered atypical Cushings?
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Dogs with C/S of Cushing's but normal ACTH and LDDST
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What are the first steps to an symptomatic dog for Cushing's but inital normal ACTH/LDDS test?
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- R/O other causes
- Repeat cortisol testing in several months - Measure adrenal steroid hormones |
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Dignosis of Atyptical Cushing's?
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Overt C/S, negative corisol testing, but positive response to TX
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What are non-secreting adrenal tumors?
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- Carcinomas
- May secrete hormones other than cortisol (progesterone & adrenal sex hormones). - These other hormones are negative feedback and cause cortisol to be low. |
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What dermatological condition maybe related to HAC?
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Alopecia X
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What 2 findings should have a sex hormone panel run?
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Adrenal mass on U/S & normal ACTH
Alopecia X |
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TX for Atypical Cushing's?
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lysodren/mitotain
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How is Atypical HAC monitored?
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ACTCH stim - goal is to supreess cortisol below theraputic levels
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Can Melatonin be used to treat atypical HAC?
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It works in normal dogs, but not proven to be effective with atypical
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What are side effects of trilostane?
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mild hyperkalemia
Addison's |
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How long dose it take for the - PU/PD
Polyphagia dermatological to resolve? |
4 weeks
4 weeks 4 months |
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How long after starting trilostaine may you see mild decrease in appetitie, and mild lethargy?
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2-4 days after starting
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How dose ketoconazole work and what condition can you use it in?
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PDH
At high concentrations, it inhibits steriod synthesis, but is hepatotoxic. start at lower dose and work up to 30 mg/kg. |
