Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
10 Cards in this Set
- Front
- Back
- 3rd side (hint)
|
Define the tubulointerstitial nephritis group diseases |
This group of renal diseases involves inflammatory injuries of the tubules and interstitium that are often insidious in onset and are principally manifest by azotemia. |
|
|
|
What are the main causes of tubulointerstitial nephritis? |
1. Infections 2. Toxins 3. Metabolic diseases 4. Physical factors 5. Neoplasms 6. Immunologic factors 7. Vascular diseases 8. Miscellanoeous |
8. Table 20-8. Rob 9. P. 929. |
|
|
What are the the main immunological reactions that cause tubulointerstitial nephritis? |
Transplant rejection Sjorgen syndrome Sarcoidosis |
3 |
|
|
What are the main causes for infections that cause tubulointerstitial nephritis? |
Acute bacterial pyelonephritis Chronic pyelonephritis , including reflux nephropathy Other infections , viruses, parasites. |
3 |
|
|
What are the 2 types of tubulointerstitial nephritis? |
Acute Chronic |
|
|
|
What is a characteristic histological picture of acute tubulointerstitial nephritis? |
Interstitial edema, Often accompanied by leukocytic infiltration of the interstitium and tubules Tubular injury |
|
|
|
What is the characteristic histological picture of chronic interstitial nephritis? |
Infiltration with mononuclear leukocytes Prominent interstitial fibrosis Wide spread tubular atrophy. |
|
|
|
What morphologic features suggest acute tubulointerstitial nephritis?
|
edemaEosinophils Neutrophils. |
|
|
|
What morphologic features are characteristic for chronic tubulointerstitial nephritis? |
Fibrosis Tubular atrophy |
|
|
|
What clinical hallmarks distinguish tubulointerstitial nephritis from the glomerular diseases? |
Absence of nephritic or nephrotic syndromes Presence of defects in tubular functions: polyuria or nocturia |
|
