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18 Cards in this Set
- Front
- Back
hemolytic-uremic syndrom
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Common in children
Causes acute renal failure Commonly caused by E.coli (O157:H7) Toxins damage endothelium, reduce NO, promote vassoconstriction and necrosis, promote thrombus - Microangiopathic hemolytic anemia |
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Wegener's granulomatosis
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Vasculitis in adults
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IgA nephropathy
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Most often in young adults.
Expanded Mesangial matrix. |
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Electron dense humps
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In post infectious GN
IgG and C3 |
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Variable thickening of BM
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Alport
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Mesangial Matrix expanded
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DM, IgA nephropathy
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post infectious GN
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IgG and C3
Electron dense humps hematuria and RBC casts |
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Amaloidosis
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proteinuria
No hematuria |
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Diabetes
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Nodular and diffuse glomeroscloeosis, leads to chronic renal failure
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PSA
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mild with prostate hyperplasia, high with carcinoma
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polycythemia
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paraneoplastic origin
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polycyctic kidney dz
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autosomal dominant
HTN Renal cell carcinoma |
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Ischemic tubular necrosis
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Rupture of tubular BM (tubulorrhexis)
1 day initiating phase, maintenance phase follows (rise in blood urea, w/ salt and water overload) Steady rise in urine output with hypokalemia |
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Fibrinoid necrosis
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malignant nephrosclerosis
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Focal segmental
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treatment is with corticosteroids, and ACE-inhibitors to control hypertension.
- hyalinosis, with a gradual progression to diffuse global glomerulosclerosis. Immunofluorescence studies show IgM and C3 deposition. - prognosis is poor, with fifty percent of patients progressing to end-stage kidney disease in five years. The prognosis is better in children. The lesion recurs in 25-50% of transplanted kidneys, indicating an extrarenal primarycause. |
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Kimmelstiel-Wilson lesion.
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Diabetic Nephropathy. poor prognosis.
Nephrotic syndrome due to this case have chronic renal failure. Treatment with ACE-inhibitors. Early detection of microalbuminuria |
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Elevated glycosylated Hgb A1c
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DM
Initially microalbinuria Progressive loss of renal fn |
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ANCA positive
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vasculitis (Wegener's)
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