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18 Cards in this Set
- Front
- Back
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adrenergic
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Norepinephrine is NT
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adrenergic receptor
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catecholamine transmitter
norepinephrine epinephrine dopamine |
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autonomic effector
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have adrenoceptors or
cholinoceptors activation --> alter fn |
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baroreceptor reflex
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- neuronal homeostatic mech
- maintains constant arterial BP - sensory limb = baroceptors of carotid sinus & aortic arch - efferent pathways in parasymp & symp nerves |
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cholinergic
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releases Ach
primary NT is Ach |
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cholinoceptor
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receptor binding Ach
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dopaminergic
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releases dopamine as NT
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parasympathetic
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- autonomic ns
- originates in cranial n & sacral cord |
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sympathetic
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- autonomic ns
- originates in thoracid & lumbar cord |
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M1
M3 |
cholinoceptor
M1 = nerve endings M3 = effector cells (smooth muscle, glands, endothelium) Gq ^ IP3 --> DAG cascade |
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M2
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cholinergic
heart, some nerve endings Gi coupled dec cAMP activates K+ channels |
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Nn
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- ANS ganglia
- ion channel --> depolarization --> AP |
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Nm
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- neuromuscular end plate
- ion channel - depolarizatin --> AP |
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alpha 1
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smooth muscle & glands
Gq ^IP3, DAG --> ^ Ca --> cxn, secretion |
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alpha 2
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nerve endings
some tissue Gi dec cAMP dec transmitter release --> cxn |
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beta 1
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cardiac muscle
juxtaglomerular apparatus Gs ^ cAMP inc HR, force, renin |
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beta 2
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smooth muscle
liver heart Gs ^ cAMP --> relax smooth muscle ^ HR, force, glycogenolysis |
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beta 3
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adipose cells
Gs ^ cAMP --> ^ lipolysis |
