Kaplan Microbiology A8

Front 1

1) What kind of organisms are Rickettsia and Chlamydia?
2) What are the 4 main diseases caused by Rickettsia?
3) What does Chlamydia cause, and it is the #1 cause of?

Back 1

1) Obligate intracellular parasites
2) Rocky Mountain spotted fever, typhus, cat scratch disease, Q fever
3) Ocular trachoma, #1 cause of STDs

Front 2

Rickettsiaceae:

1) Gram? Shape?
2) What are the 4 genera in the Rickettsiaceae family?
3) Vectors of transmission?
4) Most cause what kind of disease? Are humans a normal host?
5) DOC?

Back 2

1) Small, pleomorphic Gram - coccobacilli
2) Rickettsia, Bartonella, Coxiella, Ehrlichia
3) All by arthropods except Bartonella and Coxiella burnetii
4) Zoonotic - humans are accidental hosts, except in Chlamydia trachomatis
5) Tetracyclines

Front 3

Rocky Mountain spotted fever:

1) What organism causes it?
2) It accounts for __% of rickettsial disease in the US
3) Where is it found geographically?
4) Vectors for transmission? Reservoirs?

Back 3

1) R. rickettsii
2) 95%
3) US - south-central, eastern
4) Vector - ticks. Reservoir - rodents, dogs, ticks.

Front 4

Epidemic typhus:

1) What organism causes it?
2) Vector for transmission?
3) What is Brill-Zinsser disease?

Back 4

1) R. prowazekii
2) Human body louse
3) Recurrent form of R. prowazekii infection

Front 5

Endemic/murine typhus:

1) What organisms causes it?
2) Vector for transmission? How is it transmitted?

Back 5

1) R. typhi
2. Rat flea, feces

Front 6

Q fever:

1) What is it caused by?
2) How is it transmitted?
3) Reservoirs?
4) Clinical features?
5) Does it cause skin rash?
6) Classic presentation?

Back 6

1) Coxiella burnetii
2) No arthropod vector - inhaling infected dust, handling infected tissues, drinking contaminated milk.
3) Ticks, small wild animals, sheep, cows, goats
4) Fever/chills/headache
5) NO
6) Mild pneumonia

Front 7

Chlamydiae:

1) What are they? who do they infect?
2) What are the 3 species pathogenic for humans?
3) What are the 2 forms in the life cycle, and what are they capable of?

Back 7

1) Obligate intracellular parasites, birds and mammals.
2) C. trachomatis, C. psittaci, C. pneumoniae
3) Infectious elementary body that can't multiply. Intracellular non-infectious reticulate body that undergoes binary fission

Front 8

C. trachomatis:

1) How is it transmitted?
2) Who does it only infect?
3) What is characteristic of infected cells? What can you stain it with?

Back 8

1) Fomites, sexually, perinatally
2) Humans
3) Oval vacuolar inclusions w/ glycogen. Will stain with iodine

Front 9

C. psittaci:

1) How is it transmitted?
2) What disease does it cause?

Back 9

1) Inhaling organisms from infected birds/droppings
2) Severe pneumonia

Front 10

C. pneumoniae:

1) Who does it only infect?
2) How is it transmitted?
3) What conditions does it cause?

Back 10

1) Humans only
2) Inhalation
3) Pharyngitis, bronchitis, mild atypical pneumonia

Front 11

R. rickettsii:

1) Vector
2) Disease

Back 11

1) Tick
2) Rocky Mountain spotted fever (*rash of palms/soles moving to trunk*)

Front 12

R. prowazekii:

1) Vector
2) Disease

Back 12

1) Louse
2) Epidemic typhus (rash - trunk spreading to extremities)

Front 13

R. typhi:

1) Vector
2) Disease

Back 13

1) Flea
2) Endemic (murine) typhus

Front 14

R. tsutsugamushi

1) Vector
2) Disease

Back 14

1) Mite
2) Scrub typhus

Front 15

C. burnetii:

1) Vector
2) Disease

Back 15

1) None
2) Q fever - no rash