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Aminoglycosides examples





Gentamicin


Tobramycin


Amikacin

Actions

Bacteriocidal


Inhibits protein synthesis of many gram-negative bacteria

Indications

Treatment of severe systemic infections



Adverse effects

Ototoxicity


Nephrotoxicity


Anorexia


Nausea


Vomiting


Diarrhea

Nursing Considerations

Check 8th cranial nerve functioning (hearing)


Check renal fxn (BUN, creatinine)


Usually prescribed for 7-10 days


Encourage fluids


Small frequent meals