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62 Cards in this Set

  • Front
  • Back
!!! ---5 Major Differences in Mammalian Cleavage ---
1) *** of cell ***...
2) r*** c***
3) *** c*** d***
4) *** a*** e***
5)
1) Slowness --- division
2) Rotational Cleavage
3) Asynchrony cell division
4) Genome active early
5) Compaction
--- FIRST STAGES ---
1) *** *** region
2) *** *** zone
3) *** node
1) Koller's Sickle Region
2) Posterior Marginal Zone
3) Hensen's node
--- Chick Embryo ---
1) All inductions start from the *** *** region
2) which is found w/in the *** *** zone.
1) Koller's sickle region
2) posterior marginal zone
!!!--- Chick Embryo ---
1) Primary hypoblast cells migrate from the *** LAYER.
2) Secondary hypoblast cells migrate from the *** *** REGION
3) within the *** *** ZONE.
1) epiblast
2) Koller's sickle region
3) posterior marginal
--- Chick Embryo ---
1) *** *** is between blastoderm and yolk from
2) blastoderm cells absorbing *** *** fluid.
1) Subgerminal cavity
2) egg white
--- Chick Embryo ---
1) The head of the primitive streak is called *** ***
2) through which cells pass into the ***.
1) hensen's node
2) blastocoel
!--- Chick Embryo ---
1) Hensen's node is the head of the *** ***
2) whose center contains a ***-shaped
3) depression called the primitive ***.
1) primitive streak
2) funnel
3) pit
!!!--- Chick Embryo ---
1) Cells migrating anteriorly into *** of primitive streak
2) become foregut, ***, ***, and ***.
3) Rohde said "*** ***" cells do the migration.
1) blastocoel
2) head, mesoderm, notochord
3) Secondary hypoblast
--- Chick Embryo ---
1) The primitive streak pushes *** cells to the anterior
2) portion of the area ***, an area containing
3) *** ***(precursor of germ cells.)
1) hypoblast
2) pellucida
3) germinal crescent
--- Chick Embryo ---
1) Primitive streak retreats moving Hensen's node from center of *** ***
2) to more ***.
1) area pellucida
2) posterior
--- Chick Embryo ---
1) *** cells enclose yolk taking
2) # *** to do so.
1) Ectodermal
2) 4 days
1) ***-*** axis is established during of blastoderm cleavage
2) Barrier between ***(pH 9.5) above blastodisc
3) and *** ***(pH 6.5) below disc.
1) Dorsal-ventral
2) albumen
3) subgerminal space
!!!
1) *** and *** induce "Nodal."
2) Nodal activity initiates *** *** in PMZ.
1) Wnt8C and Vg1
2) primitive streak
*** activity initiates primitive streak.
Nodal
1) PRIMARY HYpoblast secretes ***
2) which is *** to Nodal
3) preventing it from forming the *** ***.
1) cerberus
2) antagonistic
3) primitive streak
Nodal induces primitive streak in *** ***.
posterior epiblast
1) Cerberus secreting hypoblast cells are pushed ***
2) ensure *** cells become the ***
3) rather than *** structures.
1) anteriorly
2) neural --- forebrain
3) posterior
Cerberus is an antagonist to ***.
nodal
Cerebus prevents *** from forming primitive streak.
nodal
Primary *** moves away from PMZ.
hypoblast
Fgf8 induces...
1) ***
2) ***
3) *** in epiblast.
1) ERN1
2) Sox2
3) churchill
1) Churchill induces ***
2) which blocks *** and *** causing
3) no ingression of epiblast in streak.
1) SIP1
2) Brachyury --- Tbx6
--- Gastrulation ---
1) At Hensen's node, cells are released from *** ***
2) by a # kDa protein called *** ***.
1) basal lamina
2) 190 --- scatter factor
--- Gastrulation ---
1) Scatter factor binds ***.
2) causing *** cascades
1) TKR(tyrosine kinase receptor)
2) G-protein
--- Gastrulation ---
1) *** directs movement and is present in extracellular
2) *** *** of epiblast cells at primitive streak.
1) Fibronectin
2) basal lamina
Scatter factor is secreted by *** ***.
Hensen's node
Molecular helpers involved w/blastocoel movement.
1)
2)
3)
Scatter Factor
Hyaluronic acid
Fibronectin
--- Epiboly of ECTODERMal ---
1) *** precursor cells expand outwardly to encircle the yolk.
2) Using *** *** between the two
1) Ectodermal
2) tight junctions
--- Epiboly of ECTODERMal ---
1) Upper surface *** *** cells adhere to lower
2) *** *** cells spreading along its surface.
1) area opaca
2) vitelline envelope
--- Epiboly of Ectoderm ---
1) *** is present on inner surface of vitellin envelope.
2) *** *** blocks marginal cell migration.
1) Fibronectin
2) RGD peptide
--- Gastrulation --- Epiboly of Ectoderm ---
*** cells cut from blastoderm migrate on their own.
Marginal
--- Early Mammalian Development ---
*** adheres to and enters the placenta.
Trophoblast
--- Early Mammalian Development ---
The chorion produces these three hormones essential for mammalian development...
1)
2)
3)
1) Gonadotropin
2) Progesterone
3) Chorionic somatomammotropin
--- Early Mammalian Development ---
1) ***: Peptide hormone causes placental cells to produce progesterone.
1) Gonadotropin
--- Early Mammalian Development ---
1) ***: Promotes maternal breast development during pregnancy for milk production
1) Chorionic somatomammotropin
--- Mammalian Chorion ---
1) Promote production of *** that suppress immune response of uterus.
1) lymphocytes
--- Mammalian Chorion ---
1) *** cells contain a placental-specific
2) *** antigen protecting embryo from mother.
1) Cytotrophoblast
2) histocompatible
--- Formation of Inner Cell Mass ---
***, ***, and *** are critical to ICM pathway and pluripotency.
Oct4, Stat3, and Nanog
--- Formation of Inner Cell Mass ---
Oct4 stimulate *** cells to be ICM and not ***.
morula --- trophoblast
--- Formation of Inner Cell Mass ---
1) Both *** and *** block each other causing
2) *** and *** to separate....
1) Cdx2 and Oct4
2) ICM and trophectoderm
--- Formation of Inner Cell Mass ---
*** determines what becomes trophoblast.
Cdx2
--- Formation of Inner Cell Mass ---
1) There is no *** and *** in trophectoderm.
1) Oct4 and Nanog
--- Formation of Inner Cell Mass ---
1) There is no *** in ICM.
1) Cdx2
--- Formation of Inner Cell Mass ---
All blastomeres express *** and ***.
Cdx2 and Oct4
--- Formation of Inner Cell Mass ---
Upon decision, only trophoblast have *** and ***.
Cdx2 and Nanog
--- Formation of Inner Cell Mass ---
Upon decision, only ICM have ***.
Oct4
--- Mouse Development ---
1) *** is the lytic enzyme used to make the hole embryo hatches from.
1) Strypsin
--- Derivation Schematic ---
1) *** > ICM > *** > Amniotic ectoderm
1) Blastocyst --- Epiblast
--- Human Blastocyst ---
1) Hypoblast is also known as primitive ***.
2) It separates from ICM to line *** ***.
3) giving rise to yolk sac e***.
1) endoderm
2) blastocoel cavity
3) endoderm
--- STD Human Gastrulation ---
1) Below the placenta is the *** ***(space)
2) followed by the ***
3) and *** layer of cells
4) and finally the ***(space)
1) Amniotic cavity
2) Epiblast
3) Hypoblast
4) Blastocoel
--- Human Gastrulation ---
1) *** has all the cells that will generate the embryo.
1) Epiblast
--- Human Gastrulation ---
1) Like chicks, cells migrating between epiblast and ***
2) are coated with ***.
1) hypoblast
2) hyaluronic acid
--- Human Gastrulation ---
1) Epiblast cells entering streak cease expressing *** and migrate ***.
1) E-cadherin
2) individually
--- Human Development ---
1) The chorion is membrane formed by *** mesoderm
2) and two layers of ***.
1) extraembryonic
2) trophoblast
--- Umbilical Cord ---
1) Narrow s*** from extra-embryonic mesoderm forms vessels.
1) stalk
--- Human Development ---
These layers fuse to form PLACENTA
1) Fetal ***
2) *** cells
3) Maternal *** cells
1) Chorion
2) Trophoblast
3) Decidual
--- Human Development ---
Blood vessels of Chorionic Villa grow from
1) extra-embryonic mesoderm of the *** ***(structure)
2) which is derived from *** tissue.
1) yolk sac
2) hypoblast
--- Human Chorionic Villa ---
2nd week - Secondary villus formed when underlying *** *** penetrates mounds of *** tissues called primary villus.
extra-embryonic mesoderm
cytotrophic
--- Mammalian Development ---
1) C*** is the process occurring in the
2) *** stage forming blastocoel
3) by secreting fluids by tr***.
1) Cavitation
2) morula
3) trophoblast
--- Mammalian Development ---
1) Blastocyst trophoblast AKA ***
2) become ***(structure).
1) trophectoderm
2) chorion
NC = ???
Nieuwkoop Center
Nieuwkoop Center Endoderm
1) Induces cells above to become *** ***.
2) SMO???
1) dorsal blastopore
2) Site of Blastopore Beginning