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62 Cards in this Set
- Front
- Back
!!! ---5 Major Differences in Mammalian Cleavage ---
1) *** of cell ***... 2) r*** c*** 3) *** c*** d*** 4) *** a*** e*** 5) |
1) Slowness --- division
2) Rotational Cleavage 3) Asynchrony cell division 4) Genome active early 5) Compaction |
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--- FIRST STAGES ---
1) *** *** region 2) *** *** zone 3) *** node |
1) Koller's Sickle Region
2) Posterior Marginal Zone 3) Hensen's node |
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--- Chick Embryo ---
1) All inductions start from the *** *** region 2) which is found w/in the *** *** zone. |
1) Koller's sickle region
2) posterior marginal zone |
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!!!--- Chick Embryo ---
1) Primary hypoblast cells migrate from the *** LAYER. 2) Secondary hypoblast cells migrate from the *** *** REGION 3) within the *** *** ZONE. |
1) epiblast
2) Koller's sickle region 3) posterior marginal |
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--- Chick Embryo ---
1) *** *** is between blastoderm and yolk from 2) blastoderm cells absorbing *** *** fluid. |
1) Subgerminal cavity
2) egg white |
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--- Chick Embryo ---
1) The head of the primitive streak is called *** *** 2) through which cells pass into the ***. |
1) hensen's node
2) blastocoel |
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!--- Chick Embryo ---
1) Hensen's node is the head of the *** *** 2) whose center contains a ***-shaped 3) depression called the primitive ***. |
1) primitive streak
2) funnel 3) pit |
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!!!--- Chick Embryo ---
1) Cells migrating anteriorly into *** of primitive streak 2) become foregut, ***, ***, and ***. 3) Rohde said "*** ***" cells do the migration. |
1) blastocoel
2) head, mesoderm, notochord 3) Secondary hypoblast |
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--- Chick Embryo ---
1) The primitive streak pushes *** cells to the anterior 2) portion of the area ***, an area containing 3) *** ***(precursor of germ cells.) |
1) hypoblast
2) pellucida 3) germinal crescent |
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--- Chick Embryo ---
1) Primitive streak retreats moving Hensen's node from center of *** *** 2) to more ***. |
1) area pellucida
2) posterior |
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--- Chick Embryo ---
1) *** cells enclose yolk taking 2) # *** to do so. |
1) Ectodermal
2) 4 days |
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1) ***-*** axis is established during of blastoderm cleavage
2) Barrier between ***(pH 9.5) above blastodisc 3) and *** ***(pH 6.5) below disc. |
1) Dorsal-ventral
2) albumen 3) subgerminal space |
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!!!
1) *** and *** induce "Nodal." 2) Nodal activity initiates *** *** in PMZ. |
1) Wnt8C and Vg1
2) primitive streak |
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*** activity initiates primitive streak.
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Nodal
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1) PRIMARY HYpoblast secretes ***
2) which is *** to Nodal 3) preventing it from forming the *** ***. |
1) cerberus
2) antagonistic 3) primitive streak |
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Nodal induces primitive streak in *** ***.
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posterior epiblast
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1) Cerberus secreting hypoblast cells are pushed ***
2) ensure *** cells become the *** 3) rather than *** structures. |
1) anteriorly
2) neural --- forebrain 3) posterior |
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Cerberus is an antagonist to ***.
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nodal
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Cerebus prevents *** from forming primitive streak.
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nodal
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Primary *** moves away from PMZ.
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hypoblast
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Fgf8 induces...
1) *** 2) *** 3) *** in epiblast. |
1) ERN1
2) Sox2 3) churchill |
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1) Churchill induces ***
2) which blocks *** and *** causing 3) no ingression of epiblast in streak. |
1) SIP1
2) Brachyury --- Tbx6 |
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--- Gastrulation ---
1) At Hensen's node, cells are released from *** *** 2) by a # kDa protein called *** ***. |
1) basal lamina
2) 190 --- scatter factor |
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--- Gastrulation ---
1) Scatter factor binds ***. 2) causing *** cascades |
1) TKR(tyrosine kinase receptor)
2) G-protein |
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--- Gastrulation ---
1) *** directs movement and is present in extracellular 2) *** *** of epiblast cells at primitive streak. |
1) Fibronectin
2) basal lamina |
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Scatter factor is secreted by *** ***.
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Hensen's node
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Molecular helpers involved w/blastocoel movement.
1) 2) 3) |
Scatter Factor
Hyaluronic acid Fibronectin |
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--- Epiboly of ECTODERMal ---
1) *** precursor cells expand outwardly to encircle the yolk. 2) Using *** *** between the two |
1) Ectodermal
2) tight junctions |
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--- Epiboly of ECTODERMal ---
1) Upper surface *** *** cells adhere to lower 2) *** *** cells spreading along its surface. |
1) area opaca
2) vitelline envelope |
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--- Epiboly of Ectoderm ---
1) *** is present on inner surface of vitellin envelope. 2) *** *** blocks marginal cell migration. |
1) Fibronectin
2) RGD peptide |
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--- Gastrulation --- Epiboly of Ectoderm ---
*** cells cut from blastoderm migrate on their own. |
Marginal
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--- Early Mammalian Development ---
*** adheres to and enters the placenta. |
Trophoblast
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--- Early Mammalian Development ---
The chorion produces these three hormones essential for mammalian development... 1) 2) 3) |
1) Gonadotropin
2) Progesterone 3) Chorionic somatomammotropin |
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--- Early Mammalian Development ---
1) ***: Peptide hormone causes placental cells to produce progesterone. |
1) Gonadotropin
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--- Early Mammalian Development ---
1) ***: Promotes maternal breast development during pregnancy for milk production |
1) Chorionic somatomammotropin
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--- Mammalian Chorion ---
1) Promote production of *** that suppress immune response of uterus. |
1) lymphocytes
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--- Mammalian Chorion ---
1) *** cells contain a placental-specific 2) *** antigen protecting embryo from mother. |
1) Cytotrophoblast
2) histocompatible |
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--- Formation of Inner Cell Mass ---
***, ***, and *** are critical to ICM pathway and pluripotency. |
Oct4, Stat3, and Nanog
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--- Formation of Inner Cell Mass ---
Oct4 stimulate *** cells to be ICM and not ***. |
morula --- trophoblast
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--- Formation of Inner Cell Mass ---
1) Both *** and *** block each other causing 2) *** and *** to separate.... |
1) Cdx2 and Oct4
2) ICM and trophectoderm |
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--- Formation of Inner Cell Mass ---
*** determines what becomes trophoblast. |
Cdx2
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--- Formation of Inner Cell Mass ---
1) There is no *** and *** in trophectoderm. |
1) Oct4 and Nanog
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--- Formation of Inner Cell Mass ---
1) There is no *** in ICM. |
1) Cdx2
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--- Formation of Inner Cell Mass ---
All blastomeres express *** and ***. |
Cdx2 and Oct4
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--- Formation of Inner Cell Mass ---
Upon decision, only trophoblast have *** and ***. |
Cdx2 and Nanog
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--- Formation of Inner Cell Mass ---
Upon decision, only ICM have ***. |
Oct4
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--- Mouse Development ---
1) *** is the lytic enzyme used to make the hole embryo hatches from. |
1) Strypsin
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--- Derivation Schematic ---
1) *** > ICM > *** > Amniotic ectoderm |
1) Blastocyst --- Epiblast
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--- Human Blastocyst ---
1) Hypoblast is also known as primitive ***. 2) It separates from ICM to line *** ***. 3) giving rise to yolk sac e***. |
1) endoderm
2) blastocoel cavity 3) endoderm |
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--- STD Human Gastrulation ---
1) Below the placenta is the *** ***(space) 2) followed by the *** 3) and *** layer of cells 4) and finally the ***(space) |
1) Amniotic cavity
2) Epiblast 3) Hypoblast 4) Blastocoel |
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--- Human Gastrulation ---
1) *** has all the cells that will generate the embryo. |
1) Epiblast
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--- Human Gastrulation ---
1) Like chicks, cells migrating between epiblast and *** 2) are coated with ***. |
1) hypoblast
2) hyaluronic acid |
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--- Human Gastrulation ---
1) Epiblast cells entering streak cease expressing *** and migrate ***. |
1) E-cadherin
2) individually |
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--- Human Development ---
1) The chorion is membrane formed by *** mesoderm 2) and two layers of ***. |
1) extraembryonic
2) trophoblast |
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--- Umbilical Cord ---
1) Narrow s*** from extra-embryonic mesoderm forms vessels. |
1) stalk
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--- Human Development ---
These layers fuse to form PLACENTA 1) Fetal *** 2) *** cells 3) Maternal *** cells |
1) Chorion
2) Trophoblast 3) Decidual |
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--- Human Development ---
Blood vessels of Chorionic Villa grow from 1) extra-embryonic mesoderm of the *** ***(structure) 2) which is derived from *** tissue. |
1) yolk sac
2) hypoblast |
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--- Human Chorionic Villa ---
2nd week - Secondary villus formed when underlying *** *** penetrates mounds of *** tissues called primary villus. |
extra-embryonic mesoderm
cytotrophic |
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--- Mammalian Development ---
1) C*** is the process occurring in the 2) *** stage forming blastocoel 3) by secreting fluids by tr***. |
1) Cavitation
2) morula 3) trophoblast |
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--- Mammalian Development ---
1) Blastocyst trophoblast AKA *** 2) become ***(structure). |
1) trophectoderm
2) chorion |
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NC = ???
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Nieuwkoop Center
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Nieuwkoop Center Endoderm
1) Induces cells above to become *** ***. 2) SMO??? |
1) dorsal blastopore
2) Site of Blastopore Beginning |