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37 Cards in this Set
- Front
- Back
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What are the five layer of the epidermis?
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stratum croneum, lucidun, granulosum, spinosum, basalis
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What comprises the macula adherens?
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desmosome
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What is the zona adherens?
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an intermediate junction that surround the perimeter just below the zona occludens
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What is the zona occludens?
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the tight junctions
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What is the unhappy triad?
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ACL, MCL, medial meniscus
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What is the receptor defect in acondroplasia?
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FGFR3
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Where are Bouchard's nodules?
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PIP
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Where are Heberden's nodules?
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DIP
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What do you see in osteopetrosis?
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nl serum Ca, PO4, alk phosphatase
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What do you see in osteomalacia?
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dec VitD, Ca, PO4, inc PTh
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When do you see high Ca, low PO4, high alk PO4?
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osteitis fibrosa cystica
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When do you see nl Ca, PO4, PTH, but inc alk PO4?
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Paget's Dz
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When do you see inc CK, inc aldolase, +ANA, +anti-Jo1?
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polymyositis, dermatomyositis
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Which condition has Ab to U1RNP?
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mixed CT dz
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When do you see antihistone Ab?
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drug induced lupus
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What is podagra?
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painful MTP of the big toe
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When do you see a dec in stratum granulosum?
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psoriasis
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Why should you be concerned with actinic keratosis?
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lead to squamous cell CA
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What benign bone tumor affects the proximal tibia and femur?
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osteoid osteoma (young), giant cell tumor (old)
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Where do osteoblastoma affect?
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vertebral column
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Where does enchondroma occur?
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distal extremities
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What has an t(11:22)
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Ewing's sarcoma
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What is the treatment for Buerger's Dz?
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quit smoking
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mu receptor
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morphine
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kappa receptor
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dynorphin
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delta receptor
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enkaphalin
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What is LTB4?
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neutorphil chemotactic agents
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What is LTC4,D4,E4?
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bronchoconstriction, vasoconstriction, contaction of sm muscle, inc vas perm
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What is PGI2?
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I platelet aggregation and promote vasodilation
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What is aldesleukin used for?
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renal cell Ca, metastatic melanoma
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What is EPO used for?
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anemias in renal failure
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What is filgrastim used for?
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recovery of BM
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What is sargramostim?
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recovery of BM
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What is alpha-interferon?
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Hep B and C, Kaposi sarcoma, leukemias, malignant melanoma
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What is beta-interferon?
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chronic granulomatous dz
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What is oprelvekin used for?
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thrombocytopenia
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What is thrombopoietin used for?
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thrombocytopenia
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