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21 Cards in this Set

  • Front
  • Back
252. How is Yersinia enterocolitica usually transmitted and what does it cause?
a. From pet feces (eg. Puppies)
b. Contaminated milk or pork.
c. Outbreaks of Diarrhoea!! are common in day care centres
d. Causes Mesenteric adenitis that can mimic Crohn’s or appendicitis!!!.
253. H. pylori?
a. Causes gastritis and up to 90% of duodenal ulcers.
b. Risk factor for:
1. Peptic ulcer
2. gastric adenocarcinoma
3. lymphoma.
254. H. pylori characteristics?
a. Gram negative rod
b. Urease positive (eg urease breath test)
c. Creates alkaline environment.
255. H. pylori tx?
a. Triple therapy!
1. Metronidazole, bismuth (Pepto-Bismol) and either
a. Tetracycline or amoxicillin.
2. More costly: Metronidazole, omeprazole, clarithromycin
256. Spirochetes?
a. Spiral-shaped bacteria w/axial filaments and include:
1. Borrelia (big size)
2. Leptospira
3. Treponema
b. Only Borrelia can be visualized using aniline dyes (Wright’s or Giemsa stain) in light microscopy.
257. How is Treponema visualized?!?! (syphilis)
a. Dark-field microscopy.
258. Leptospira Interrogans?
a. Question mark-shaped bacteria found in water contaminated with animal urine.
259. Leptospirosis sx?
a. Flu-like sx.
b. Fever
c. HA
d. Abdominal pain
e. Jaundice
f. Photophobia with conjunctivitis.
g. Most prevalent among surfers in the tropics.
260. Weil’s disease?
a. Icterohemorrhagic leptospirosis
b. Severe form w/jaundice and azotemia from liver and kidney dysfunction
c. Fever, haemorrhage, anaemia.
261. Cause of Lyme disease?
a. Borellia burgdorferi, transmitted by the Ixodes tick (also vector for Babesia).
b. Mice are important reservoirs.
c. Deer required for tick life cycle.
262. Presentation of Lyme disease?
a. Presents w/erythema chronicum migrans
b. Expanding bull’s eye red rash w/central clearing.
c. Affects joints, CNS, and heart.
263. 3 stages of Lyme disease?
a. Stage 1: erythema chronicum migrans, flu-like symptoms.
b. Stage 2: Neurologic (Bell’s palsy) and cardiac (AV nodal block) manifestation.
c. Stage 3: Chronic monoarthritis, and migratory polyarthritis.
264. Syphilis cause?
a. Treponema pallidum.
265. Primary syphilis presents with?
a. Painless chancre (localized disease)
b. Tx. Penicillin G.
266. Secondary syphilis presents with?
a. Disseminated disease w/constitutional symptoms:
i. Maculopapular rash (Palms and soles)
ii. Condylomata latea.
iii. May treponemes are present in chancres of primary and condylomata lata of secondary syphilis.
b. Secondary = systemic.
267. Tertiary syphilis presents with?
a. Gummas (chronic granulomas)
b. Aortitis (vasa vasorum destruction)
c. Neurosyphilis (tabes dorsalis)
d. Argyll Robertson pupil.
268. Signs of Tertiary syphilis on PE?
a. Broad-based ataxia
b. Positive Romberg
c. Charcot joint
d. Stroke w/out HTN.
269. Screen and Confirm for syphilis?
a. Screen: VDRL
b. Confirm with: FTA-ABS (uses Abs specific for Treponema pallidum).
270. Congenital syphilis?
a. Saber shins
b. Saddle nose
c. CN VIII deafness
d. Hutchinson’s teeth
e. Mulberry molars.
271. Argyll Robertson Pupil?
a. Accommodates but doesn’t react.
b. Associated w/tertiary syphilis
272. VDRL false positives?
a. VDRL detects nonspecific antibodies that rect w/beef cardiolipin.
b. Used for syphilis but false positives include:
1. Viruses (mono, hepatitis)
2. Drugs
3. Rheumatic fever
4. Lupus and Leprosy
c. VDRL^.