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22 Cards in this Set

  • Front
  • Back
235. Polyarteritis nodosa?
a. Immune complex-mediated transmural vasculitis w/fibrinoid necrosis.
236. Sx of polyarteritis nodosa?
1. Fever
2. Wt. loss
3. Malaise
4. Abdominal pain
5. Melena
6. HA
7. Myalgia
8. HTN
9. Neurologic dysfunction
10. Cutaneous eruptions.
237. Findings in polyarteritis nodosa?
a. Hepatitis B seropositive in 30% of patients!!!!
b. Multiple aneurysms and constrictions on arteriogram.
238. Tx of polyarteritis nodosa?
a. Corticosteroids
b. Cyclophosphamide.
Condition you better not forget is associated w/polyarteritis nodosa?
Hep B
239. Significant feature of Polyarteritis Nodosa- What is spared and how does the age of the lesions compare?
a. Typically involves renal and visceral vessels NOT pulmonary arteries.
b. Lesions are at different ages.
240. Takayasu’s arteritis?
a. Known as “Pulseless disease”.
b. Granulomatous thickening of aortic arch and/or proximal great vessels.
c. Associated w/an ↑ ESR.
d. Primarily affects Asian females < 40 yo.
241. Sx of Takayasu’s arteritis?
a. Fever
b. Arthritis
c. Night sweats
d. Myalgia
e. SKIN nodules
f. Ocular disturbances
g. Weak pulses in upper extremities.
242. Temporal arteritis (Giant cell arteritis)?
+
Key Feature to look for?
a. Most common vasculitis affecting medium and large arteries.
b. Usually branches of carotid artery
c. Focal, granulomatous inflammation.
d. Affects elderly females.
243. Sx of temporal arteritis?
a. Unilateral HA
b. Jaw claudication
c. Impaired vision (occlusion of ophthalmic artery that may lead to irreversible blindness).
244. Findings associated w/temporal arteritis?
a. ↑ ESR.
b. Half of pts have systemic involvement and poly myalgia rheumatica.
245. Strawberry hemangioma (vascular tumour)?
a. Benign capillary hemangioma of infancy.
b. Initially grows w/child!!
c. Then spontaneously regresses.

So first grows then regresses- had a question on this.
246. Cherry hemangioma (vascular tumour)?
a. Benign capillary hemangioma of elderly. (Think elderly prefer cherries while children prefer strawberries)
b. Does not regress
c. Frequency ↑ w/age.
247. Pyogenic granuloma (vascular tumour)?
a. Polypoid capillary hemangioma that can ulcerate and bleed.
b. Associated w/trauma and pregnancy.
248. Cystic hygroma (vascular tumour)?
a. Cavernous lymphangioma of the neck.
b. Associated w/Turner syndrome.
249. Glomus tumour (vascular tumour)?
a. Benign, painful, red-blue tumour under fingernails.
b. Arises w/modified smooth muscle cells of glomus body
What are the cells of the Glomus Tumour (under the fingernail) important for?!?
had a question on this
Thermoregulation.
250. Bacillary angiomatosis (vascular tumour)?
a. Benign capillary skin papules found in AIDS pts.
b. Caused by Bartonella Henselae infections.
c. Frequently mistaken for Kaposi’s sarcoma.
251. Angiosarcoma?
a. Highly lethal malignancy of the liver.
b. Associated w/vinyl chloride, arsenic, and ThO2 (thorotrast) exposure.
252. Lymphangiosarcoma?
a. Lymphatic malignancy associated w/persistent lymphedema (e.g. post-radical mastectomy).
253. Kaposi’s sarcoma?
a. Endothelial malignancy of the skin associated w/HHV-8 and HIV.
b. Frequently mistaken for bacillary angiomatosis.
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